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Antimicrobials: Healthcare's Silver Bullet Against HAIs?

By Kelly M. Pyrek
08/28/2008
Continued from page 20

Some may wonder if the continued widespread use of antibacterial agents could lead to more resistant bacteria. According to the APUA, “Many scientists feel that this is a potential danger, but others argue that the laboratory conditions used in the research studies do not represent the real world. So far, studies of antibacterial use in home products such as soap, deodorant and toothpaste have not shown any detectable development of resistance. However, such products have only been in use for a relatively short period of time and studies of their effects are still extremely limited.”

Child (2005) emphasizes that antimicrobial products and treatments “must not undermine the success of traditional hygiene methods and neither must conventional cleaning and hygiene operations be relaxed if antimicrobial coatings are employed.” 

References:

APUA. Tufts University’s Alliance for the Prudent Use of Antibiotics. http://www.tufts.edu/med/apua/Practitioners/healthcare.html and http://www.tufts.edu/med/apua/Q&A/Q&A_antibacterials.html

Child T. Antimicrobial surfaces. 2005. Accessed at http://www.allbusiness.com/asia/484476-1.html

Gibbins B and Warner L. Surface treatments: The role of antimicrobial silver nanotechnology. Medical Device & Diagnostic Industry. August 2005.

Dresher WH. Copper Applications in Health & Environment Area. August 2004. Accessed at: http://www.copper.org/publications/newsletters/innovations/2004/08/copper_helps_control_infection_in_healthcare_facilities.html

Noyce J, Michels H and Keevil C. Potential use of copper surfaces to reduce survival of epidemic meticillin-resistant Staphylococcus aureus in the healthcare environment. J Hosp Infection. Vol. 63, No. 3, Pp 289-297.

Noyce, JO and CW Keevil. The antimicrobial effects of copper and copper alloys on methicillin-resistant Staphylococcus aureus. Presented at the American Society of Microbiology, May 2004.

Pearson ML and Abrutyn E. Reducing the risk for catheter-related infections: A new strategy. Ann Intern Med. August 15, 1997. Vol. 127, No. 4. Pp. 304-306.

Maki DG, Stolz SM, Wheeler S, Mermel LA. Prevention of central venous catheter-related bloodstream infection by use of an antiseptic-impregnated catheter. A randomized, controlled trial. Ann Intern Med. 1997;127:257-66.

Raad I, Darouiche R, Dupuis J, Abi-Said D, Gabrielli A, Hachem R, et al. Central venous catheters coated with minocycline and rifampin for the orevention of catheter-related colonization and bloodstream infections. A randomized, double-blind trial. Ann Intern Med. 1997;127:267-74.

Rupp ME, Lisco SJ, Lipsett PA, Perl TM, Keating K, Civetta JM, Mermel LA, Lee D, Dellinger EP, Donahoe M, Giles D, Pfaller MA, Maki DG, and Sherertz R. Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections. Ann Intern Med. 2005;143:570-580.

Darouiche RO. Antimicrobial approaches for preventing infections associated with surgical implants. Clin Infect Diseases. May 15, 2003:36.

Ip M, Lui SL, Poon VK, Lung I, Burd A. Antimicrobial activities of silver dressings: an in vitro comparison. J Med Microbiol 55 (2006), 59-63.

Thomas S and McCubbin P. A comparison of the antimicrobial effects of four silver-containing dressings on three organisms. 1: J Wound Care. 2003 Mar;12(3):101-7.

Parsons D, Bowler PG, Myles V, Jones S. Silver antimicrobial dressings in wound management: A comparison of antibacterial, physical, and chemical characteristics. Medscape.com. Oct. 4, 2005.

Kuhn PJ. Doorknobs: A source of nosocomial infection? Diag. Med. Nov/Dec. 1983. Accessed at: http://www.copper.org/health/papers/doorknob.html

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