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Oral Vitamin D May Help Prevent Some Skin Infections

10/06/2008

A study led by researchers at the University of California, San Diego School of Medicine suggests that use of oral vitamin D supplements bolsters production of a protective chemical normally found in the skin, and may help prevent skin infections that are a common result of atopic dermatitis, the most common form of eczema.

The study – led by Richard Gallo, MD, PhD, professor of medicine and chief of the Division of Dermatology at the UCSD School of Medicine and the Dermatology section of the Veterans Affairs San Diego Healthcare System, and Tissa R. Hata, MD, associate professor of medicine at UC San Diego – found that use of oral vitamin D appeared to correct a defect in the immune systems in patients with this skin disease. Their findings will be published in the October 3 edition of the Journal of Allergy & Clinical Immunology.

The researchers studied a small number of patients with moderate to severe atopic dermatitis, a chronic skin disease that affects 10 to 20 percent of children and 1 percent to 3 percent of adults. Atopic dermatitis is characterized by areas of severe itching, redness and scaling. Over time, chronic changes can occur due to constant scratching and rubbing. The condition puts patients at increased risk for skin infections by Staphylococcus aureus and the herpes and smallpox viruses.

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