Clostridium Difficile

Clostridium difficile (C. diff) is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. Clostridium difficile is shed in feces. Any surface, device, or material that becomes contaminated with feces may serve as a reservoir for the Clostridium difficile spores. Clostridium difficile spores are transferred to patients mainly via the hands of healthcare personnel who have touched a contaminated surface or item. Clostridium difficile infection be prevented in hospitals by the prudent use of antibiotics; the use of contact precautions for patients with known or suspected Clostridium difficile infection; preventing contamination of the hands via glove use and handwashing; and implement an environmental cleaning and disinfection strategy.


  • Clostridium difficile Infection: Tracking a Virulent Pathogen
    The rates and severity of Clostridium difficile infection (CDI) may be impacted by several factors, including antimicrobial use, other drug-prescribing factors, infection control practices, and the presence of a new strain of C. difficile that is more resistant to ...More
    August 13, 2009 Posted in News
  • Could Ramoplanin be the Next Vancomycin?
    With the "last resort" antibiotic Vancomycin now plagued by the first signs of bacterial resistance, a scientific collaboration centered at Duke University has identified how a candidate successor antibiotic known as Ramoplanin A2 can kill pathogenic bacteria by ...More
    August 3, 2009 Posted in News
  • Sanitizer Automates Disinfection of Hard-to-Clean Hospital Equipment
    At right: The SUDS sanitizer.Johns Hopkins experts in applied physics, computer engineering, infectious diseases, emergency medicine, microbiology, pathology and surgery have unveiled a 7-foot-tall, $10,000 shower-cubicle-shaped device that automatically sanitizes in 30 ...More
    July 31, 2009 Posted in News, Disinfection & Sterilization, Hand Hygiene
  • C. difficile Spores Spread Superbug
    New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of ...More
    July 20, 2009 Posted in News, Environmental Hygiene
  • Tru-D: Proactive, Effective, Thorough, Fast, Proven
    This article is part of the UV Light Product Showcase that was featured in the July 2009 issue of ICT.Clinical trials conclude that Tru-D exceeds all disinfection requirements for pathogen log reduction of high-touch surfaces for vancomycin-resistant Enteroccoci (VRE), ...More
  • Antibiotics Take Toll on Beneficial Microbes in Gut
    In mice, University of Michigan researcher Vincent B. Young found that gut microflora were significantly altered after antibiotics.   It’s common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least ...More
    June 18, 2009 Posted in News
  • APIC Launches Online Infection Prevention Course
    The first of six online courses to educate healthcare professionals on preventing the transmission of healthcare-associated infections (HAIs) is being launched by the Association for Professionals in Infection Control and Epidemiology (APIC).  Healthcare-associated ...More
    June 2, 2009 Posted in News
  • Selenium Could be Key to Developing New Antibiotics
    A mineral found at health food stores could be the key to developing a new line of antibiotics for bacteria that commonly cause diarrhea, tooth decay and, in some severe cases, death.The trace mineral selenium is found in a number of proteins in both bacterial cells and ...More
    June 1, 2009 Posted in News
  • How to Select an Ideal Disinfectant
    This article appeared in the June 2009 issue of ICT in the How to Do Anything Better Guide.With the emergence of antibiotic-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), etc. and more virulent strains ...More
  • Control of Resistant Bacteria in Outpatient Clinics
    While infections with antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile (C. difficile) and vancomycin-resistant Enterococcus, are usually associated with inpatient settings, the potential for infection in ...More
    May 11, 2009 Posted in News