Clostridium Difficile

Clostridium difficile (C. diff) is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. Clostridium difficile is shed in feces. Any surface, device, or material that becomes contaminated with feces may serve as a reservoir for the Clostridium difficile spores. Clostridium difficile spores are transferred to patients mainly via the hands of healthcare personnel who have touched a contaminated surface or item. Clostridium difficile infection be prevented in hospitals by the prudent use of antibiotics; the use of contact precautions for patients with known or suspected Clostridium difficile infection; preventing contamination of the hands via glove use and handwashing; and implement an environmental cleaning and disinfection strategy.


  • New Guidelines for Diagnosing, Managing and Treating Clostridium difficile
    A joint panel of experts from the Society for Healthcare Epidemiology (SHEA) and the Infectious Diseases Society of America (IDSA) today released online new clinical practice guidelines for Clostridium difficile infection (CDI) in adults. The guidelines, to be published in ...More
    March 22, 2010 Posted in News
  • Intervention Drops Hospital Infection Rate by One-Third
    Clostridium difficile (C. difficile) is the one of the leading pathogens causing hospital-acquired infection in the United States. It may cause diarrhea, colitis, sepsis and lead to prolonged hospitalization and death. Mayo Clinic researchers say they've found a way to ...More
  • Studies Show Significant Increases of C. difficile Infections
    Clostridium difficile infections (CDIs) are quickly becoming a significant issue in healthcare based upon recent studies. Preliminary data collected from nursing homes and highlighted in a Supplementary Pennsylvania Patient Safety Advisory shows that almost 40 percent of ...More
    March 20, 2010 Posted in News
  • Active Surveillance Cultures: Friend or Foe?
    Part one of a two-part series.Whether or not it is mandated by state law, some healthcare institutions are turning to active surveillance cultures (ASC) of all or certain high-risk patients, as well as placing them under contact precautions – all in an effort to curb ...More
    March 17, 2010 Posted in Articles
  • Molnlycke Health Care Introduces New Hibiclens General Skin Cleansing Patient Kit
    Molnlycke Health Care U.S., manufacturer of Hibiclens® antiseptic antimicrobial skin cleanser, introduces a General Skin Cleansing Patient Kit to be used at home prior to surgery as part of an effective strategy to fight surgical-site infections (SSIs) and ...More
    March 17, 2010 Posted in News
  • Researchers Describe How Cholera Bacteria Becomes Infectious
    In a new study, Dartmouth researchers describe the structure of a protein called ToxT that controls the virulent nature of Vibrio cholerae, the bacteria that causes cholera. Buried within ToxT, the researchers were surprised to find a fatty acid that appears to inhibit ...More
    February 12, 2010 Posted in News
  • C. Diff Infection Rising in Community Settings, Study Finds
    Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. ...More
    October 26, 2009 Posted in News
  • HHS Awards $17 Million in New Initiative to Fight HAIs
    HHS Secretary Kathleen Sebelius has announced the award of $17 million to fund projects to fight costly and dangerous healthcare-associated infections (HAIs). "When patients go to the hospital, they expect to get better, not worse," Sebelius said. "Eliminating infections is ...More
    October 26, 2009 Posted in News
  • Control and Prevention of MDROs
    While multidrug-resistant organisms (MDROs) such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), Clostridium difficile (C. diff) and certain Gram-negative bacilli (GNB ) continue to alarm the general public and are frequently ...More
    October 15, 2009 Posted in Articles
  • HAI Prevention Programs Require Better Adherence to Proven Strategies
    When the Department of Health and Human Services (HHS) issued its “Action Plan To Prevent Healthcare-Associated Infections,” earlier this year, it not only cast new attention on this old problem, but it helped identify the key actions needed to achieve and ...More
    September 24, 2009 Posted in Articles