Clostridium Difficile

Clostridium difficile (C. diff) is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. Clostridium difficile is shed in feces. Any surface, device, or material that becomes contaminated with feces may serve as a reservoir for the Clostridium difficile spores. Clostridium difficile spores are transferred to patients mainly via the hands of healthcare personnel who have touched a contaminated surface or item. Clostridium difficile infection be prevented in hospitals by the prudent use of antibiotics; the use of contact precautions for patients with known or suspected Clostridium difficile infection; preventing contamination of the hands via glove use and handwashing; and implement an environmental cleaning and disinfection strategy.


  • BioMérieux’s 2010 Odyssey Hits the Road in the Battle Against Superbugs
    BioMérieux, a leader in the field of in vitro diagnostics, begins its sixth tour across the United States and Canada to provide industry professionals with innovative training in advanced diagnostics solutions that can improve public health in the fight against ...More
    April 26, 2010 Posted in News
  • Researchers Study Vaccine to Prevent C. diff Outbreaks
    The thought of being infected with MRSA brings fear and panic to those who know how fatal the flesh-eating bacterial infection can be. Now, recent reports show that a known bacterium is overtaking numbers of MRSA infections in hospital settings, making physicians ...More
    April 12, 2010 Posted in News
  • Vancouver Hospital Struggles with C. diff Outbreak
    The Vancouver Sun and Canwest News Service are reporting that eight patients at Nanaimo Regional General Hospital have become ill from Clostridium difficile infections and one patient may have already died from the infection.  Reporter Richard Watts says that as ...More
    April 8, 2010 Posted in News
  • C. diff Surpassing MRSA Infections in Community Hospitals
    While prevention methods appear to be helping to lower hospital infection rates from MRSA, a deadly antibiotic-resistant bacterium, a new superbug is on the rise, according to research from the Duke Infection Control Outreach Network.New data shows infections from ...More
    March 22, 2010 Posted in News
  • New Guidelines for Diagnosing, Managing and Treating Clostridium difficile
    A joint panel of experts from the Society for Healthcare Epidemiology (SHEA) and the Infectious Diseases Society of America (IDSA) today released online new clinical practice guidelines for Clostridium difficile infection (CDI) in adults. The guidelines, to be published in ...More
    March 22, 2010 Posted in News
  • Intervention Drops Hospital Infection Rate by One-Third
    Clostridium difficile (C. difficile) is the one of the leading pathogens causing hospital-acquired infection in the United States. It may cause diarrhea, colitis, sepsis and lead to prolonged hospitalization and death. Mayo Clinic researchers say they've found a way to ...More
  • Studies Show Significant Increases of C. difficile Infections
    Clostridium difficile infections (CDIs) are quickly becoming a significant issue in healthcare based upon recent studies. Preliminary data collected from nursing homes and highlighted in a Supplementary Pennsylvania Patient Safety Advisory shows that almost 40 percent of ...More
    March 20, 2010 Posted in News
  • Active Surveillance Cultures: Friend or Foe?
    Part one of a two-part series.Whether or not it is mandated by state law, some healthcare institutions are turning to active surveillance cultures (ASC) of all or certain high-risk patients, as well as placing them under contact precautions – all in an effort to curb ...More
    March 17, 2010 Posted in Articles
  • Molnlycke Health Care Introduces New Hibiclens General Skin Cleansing Patient Kit
    Molnlycke Health Care U.S., manufacturer of Hibiclens® antiseptic antimicrobial skin cleanser, introduces a General Skin Cleansing Patient Kit to be used at home prior to surgery as part of an effective strategy to fight surgical-site infections (SSIs) and ...More
    March 17, 2010 Posted in News
  • Researchers Describe How Cholera Bacteria Becomes Infectious
    In a new study, Dartmouth researchers describe the structure of a protein called ToxT that controls the virulent nature of Vibrio cholerae, the bacteria that causes cholera. Buried within ToxT, the researchers were surprised to find a fatty acid that appears to inhibit ...More
    February 12, 2010 Posted in News