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Fungal Infections

  • Newly Found Immune Deficiency Opens the Door to Fungal Infections, Bacterial Disease
    When a genetic error weakens a child's immunity, otherwise nonthreatening microbes can sicken and sometimes kill. In work published July 9 in Science, researchers at Rockefeller University and their colleagues identify one surprising case in which mutations in a single gene ...More
    July 10, 2015 Posted in News
  • Study Provides New Insights Into the Genetics of Drug-Resistant Fungal Infections
    A study by a multidisciplinary research team, co-directed by Worcester Polytechnic Institute (WPI), offers new insights into how virulent fungi adapt through genetic modifications to fight back against the effects of medication designed to block their spread, and how that ...More
    July 6, 2015 Posted in News
  • CRISPR-Cas Editing of C. albicans Holds Promise for Overcoming Deadly Fungal Infections
    By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a ...More
    April 3, 2015 Posted in News
  • How a Deadly Fungus Evades the Immune System
    New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most common causes of bloodstream infections. Previously, scientists ...More
    March 31, 2015 Posted in News
  • FDA Approves New Antifungal Drug Cresemba
    The Food and Drug Administration today approved Cresemba (isavuconazonium sulfate), a new antifungal drug product used to treat adults with invasive aspergillosis and invasive mucormycosis, rare but serious infections. Aspergillosis is a fungal infection caused by ...More
    March 9, 2015 Posted in News
  • Drug Combinations a Good Approach for Infectious Fungus, Research Shows
    Researchers at the University of Toronto have discovered that Candida albicans -- a leading cause of potentially fatal hospital-acquired infections -- rarely develops resistance to combination drug therapy and, when it becomes resistant, it also becomes less dangerous. The ...More
    February 6, 2015 Posted in News
  • CDC, FDA Investigating Fatal Gastrointestinal Mucormycosis in an Infant
    The Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA) and the Connecticut Departments of Public Health and Consumer Protection are investigating a fatal case of gastrointestinal (GI) mucormycosis caused by Rhizopus oryzae in a ...More
    December 4, 2014 Posted in News
  • Breath Test Shows Promise for Diagnosing Fungal Pneumonia
    Many different microbes can cause pneumonia, and treatment may be delayed or off target if doctors cannot tell which bug is the culprit. A novel approach—analyzing a patient’s breath for key chemical compounds made by the infecting microbe—may help detect ...More
    October 23, 2014 Posted in News
  • Novel Trick Helps Rare Pathogen Infect Healthy People
    New research into a rare pathogen has shown how a unique evolutionary trait allows it to infect even the healthiest of hosts through a smart solution to the body's immune response against it. Scientists at the University of Birmingham have explained how a particular strain ...More
    October 20, 2014 Posted in News
  • New Antifungal as Effective as Existing Drugs With Fewer Adverse Events
    A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole, against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data presented at the 54th Interscience Conference on Antimicrobial ...More
    September 8, 2014 Posted in News
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