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Fungal Infections

  • First Outbreak of the Globally Emerging Candida auris in a European Hospital
    Candida auris is a globally emerging multidrug-resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016. This is the first report of C. auris in Europe and the ...More
    2 weeks ago Posted in News
  • Rutgers Team Awarded Contract by CDC to Better Understand, Combat Fungal Infections
    A team of researchers led by David S. Perlin, PhD, at the Public Health Research Institute (PHRI), a unit of the New Jersey Medical School and Rutgers University, has been awarded a $300,000 contract by the Centers for Disease Control and Prevention (CDC) to investigate ...More
    3 weeks ago Posted in News
  • Team Identifies Fungus in Humans for First Time as Key Factor in Crohn's Disease
    A Case Western Reserve University School of Medicine-led team of international researchers has for the first time identified a fungus as a key factor in the development of Crohn’s disease. The researchers also linked a new bacterium to the previous bacteria associated ...More
    September 27, 2016 Posted in News
  • Fighting Penicilliosis
    Penicilliosis, caused by the fungus Talaromyces marneffei, is a major opportunistic infection in Southeast Asia. A study published in PLOS Neglected Tropical Diseases reports that the fungal protein Mp1p is responsible for the pathogen's ability to cause disease in mice, ...More
    August 25, 2016 Posted in News
  • Disrupting Mitochondrial Function Could Improve Treatment of Fungal Infections
    By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today’s most commonly ...More
    August 11, 2016 Posted in News
  • Valley Fever Diagnosis Often Missed
    For patients with pneumonia or ongoing influenza-like symptoms who live in or have visited the west or southwest United States, especially Arizona and central California, infectious diseases experts recommend physicians suspect valley fever, an often-overlooked fungal ...More
    July 28, 2016 Posted in News
  • Research Offers New Hope for Understanding Deadly Infections
    Research published today in the journal, Nature Communications, provides new insights into the evolution of Mucorales fungi, which cause a fatal infection in ever-increasing segments of patient population, and several molecular pathways that might be exploited as potential ...More
    July 21, 2016 Posted in News
  • Scientists Find a New Way to Protect Against Lethal Fungal Infections
    For most people, a simple case of thrush or athlete’s foot can be quickly and easily treated using over-the-counter anti-fungal creams and pills. However, even with medication, fungal pathogens can overwhelm a weakened immune system and cause systemic infections ...More
    July 18, 2016 Posted in News
  • Chemical Structure Paves the Way for New Broad-Spectrum Antifungals
    Fungal infections can be devastating to human health, killing approximately 150 people every hour, resulting in more than 1 million deaths every year, more than malaria and tuberculosis combined. Unfortunately the antifungal drug arsenal is limited, with many of the ...More
    June 14, 2016 Posted in News
  • Angina Drug Could Inform a New Strategy to Fight Cryptococcosis
    A drug more commonly used in the treatment of angina could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis. Researchers from the University of Birmingham found that the compound fendiline hydrochloride could be used to stimulate a ...More
    June 7, 2016 Posted in News