Gram-Negative Bacteria

Researchers Study MDR GNB Colonization of Healthy Military Personnel in the U.S., Afghanistan

The U.S. military has seen steady increases in multidrug-resistant (MDR) gram-negative bacteria (GNB) infections in casualties from Iraq and Afghanistan. Vento, et al. (2013) evaluated the prevalence of MDR GNB colonization in U.S. military personnel. GNB colonization ...More
February 6, 2013
Posted in News
Synthetic Corkscrew Peptide Kills Antibiotic-Resistant Gram-Negative Bacteria

An engineered peptide provides a new prototype for killing an entire category of resistant bacteria by shredding and dissolving their double-layered membranes, which are thought to protect those microbes from antibiotics. The synthetic peptide was effective in lab ...More
January 24, 2013
Posted in News
Discovery of Bacteria Survival Trick Opens Door to New Kinds of Therapeutics

Learning the secrets of how pathogenic bacteria manage to survive in the body of an animal or human may carry great implications for future development of new and better medical treatments. Now, scientists at the University of Maryland School of Dentistry have unraveled one ...More
June 11, 2012
Posted in News
Paper Describes Novel Anti-Infective Agent Against Both Gram-Positive and Negative Pathogens

The current public health war against bacterial infections is rapidly approaching a critical stage, in which bacterial resistance to antibiotics becomes widespread and our reservoirs of available antibiotics and viable therapeutics are depleted. During the past 60 years, ...More
November 14, 2011
Posted in News
Survey Reveals ID Specialists' Therapy Choice for Treatment of Gram-Negative Infections

Decision Resources, a research and advisory firm for pharmaceutical and healthcare issues, finds that the majority (65 percent) of surveyed U.S. infectious disease specialists chose Merck’s Primaxin/Tienam (imipenem/cilastatin) as the most efficacious therapy for the ...More
March 29, 2011
Posted in News
Researchers Examine Outcome of Necrotizing Fasciitis Depending on the Pathogen

Monomicrobial necrotizing fasciitis is rapidly progressive and life-threatening. Ching-Yu Lee, of the Department of Orthopedic Surgery at Chang Gung Memorial Hospital in Taiwan, and colleagues, sought to ascertain whether the clinical presentation and outcome for patients ...More
January 5, 2011
Posted in News
Insulin May Reduce Several Inflammatory Factors Induced by Bacterial Infection

Treating intensive care patients who develop life-threatening bacterial infections, or septicemia, with insulin potentially could reduce their chances of succumbing to the infection, if results of a new preliminary study can be replicated in a larger study. A paper ...More
September 9, 2010
Posted in News
Swift Actions Stop Outbreak at Dallas Hospital

Rapid identification and aggressive infection control measures allowed a Dallas hospital to stop the spread of Acinetobacter baumannii. ...More
July 13, 2010
Posted in News
Scientists Crack Code of Critical Bacterial Defense Mechanism

By Emily CaldwellScientists have combined chemistry and biology research techniques to explain how certain bacteria grow structures on their surfaces that allow them to simultaneously cause illness and protect themselves from the body’s defenses.The researchers are ...More
April 26, 2010
Posted in News
Control and Prevention of MDROs

While multidrug-resistant organisms (MDROs) such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), Clostridium difficile (C. diff) and certain Gram-negative bacilli (GNB ) continue to alarm the general public and are frequently ...More
October 15, 2009
Posted in Articles