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Immune Response

  • Persistent Bacterial Infection Exploits Killing Machinery of Immune Cells
    A new study reveals an important and newly discovered pathway used by disease-causing bacteria to evade the host immune system and survive and grow within the very cells meant to destroy them. This discovery may lead to new treatments and vaccines for tuberculosis (TB) and ...More
    November 3, 2008 Posted in News
  • How HIV Vaccine Might Have Increased Odds of Infection
    In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection. A new study by a team of researchers at the Montpellier Institute of Molecular Genetics in France shows how ...More
    November 3, 2008 Posted in News
  • Gene Against Bacterial Attack is Unraveled
    Dutch researcher and physician Joost Wiersinga from AMC Medical Centre in Amsterdam has unraveled a genetic defense mechanism against the lethal bacteria Burkholderia pseudomallei. The research is the next step toward a vaccine against this bacterium suitable for ...More
    October 28, 2008 Posted in News
  • Researchers Identify Novel Type of Antibody that Potently Inhibits HIV Infection
    A small antibody fragment that is highly effective in neutralizing the human immunodeficiency virus (HIV) by preventing the virus from entering cells has been identified by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). ...More
    October 21, 2008 Posted in News
  • Researchers Shed Light on Immune System Suppression
    New work reported in the Oct. 16 issue of the journal Cell Host & Microbe.from researchers at the Scripps Institute Work could aid development of new treatments for infectious diseases such as HIV, measles and tuberculosis. The study described the suppression of this ...More
    October 20, 2008 Posted in News
  • Scientists Discover Crucial Control in Long-Lasting Immunity After Infection
    National Institutes of Health (NIH) scientists have identified a protein that plays matchmaker between two key types of white blood cells, T and B cells, enabling them to interact in a way that is crucial to establishing long-lasting immunity after an infection. Their ...More
    October 13, 2008 Posted in News
  • DNA of Good Bacteria Drives Intestinal Response to Infection
    A new study shows that the DNA of so-called "good bacteria" that normally live in the intestines may help defend the body against infection. The findings, available Oct. 2 online in the journal Immunity, are reported by Yasmine Belkaid, PhD, and her colleagues in the ...More
    October 4, 2008 Posted in News
  • Scientists Unmask Key HIV Protein, Open Door for New AIDS Drugs
    At left, a normal, uninfected cell with green-stained MHC-I protein on the cell surface. At right, an HIV infected cell -- most of the MHC-I builds up inside, keeping the cell from telling the immune system that it harbors a virus. Source: University of Michigan  ...More
    September 29, 2008 Posted in News
  • “Friendly” Bacteria Protect Against Type 1 Diabetes, Yale Researchers Find
    In a dramatic illustration of the potential for microbes to prevent disease, researchers at Yale University and the University of Chicago showed that mice exposed to common stomach bacteria were protected against the development of Type I diabetes.The findings, reported in ...More
    September 22, 2008 Posted in News
  • Herpes Virus Changes Anti-Herpes Drug to Form that Hinders AIDS Virus
    The drug acyclovir has long been used to suppress outbreaks of oral and genital herpes. Herpes viruses change acyclovir to a form that prevents them from reproducing. Now, it appears that after acyclovir is altered by herpes viruses, it also interferes with the AIDS ...More
    September 11, 2008 Posted in News