Immune System


  • Antibodies Take 'Evolutionary Leaps' to Fight Microbes
    A new report in the January 2009 issue of the FASEB Journal explains for the first time how humans keep up with microbes by rearranging the genes that make antibodies to foreign invaders. This research fills a significant gap in our understanding of how the immune system ...More
    January 5, 2009 Posted in News
  • Peering Inside the Skull of a Mouse to Solve Meningitis Mystery
    NYULangoneMedicalCenter scientists and their collaborators at the Scripps Research Institute in La Jolla, Calif., have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous system, according to a study ...More
    December 22, 2008 Posted in News
  • Immunity Stronger at Night Than During the Day
    The immune system's battle against invading bacteria reaches its peak activity at night and is lowest during the day. Experiments with the laboratory model organism, Drosophila melanogaster, reveal that the specific immune response known as phagocytosis oscillates with the ...More
    December 15, 2008 Posted in News
  • Mathematical Models of Adaptive Immunity
    More than 5 million people die every year from infectious diseases, despite the availability of numerous antibiotics and vaccines. The discovery of penicillin to treat bacterial infections, along with the development of vaccines for previously incurable virus diseases such ...More
    December 11, 2008 Posted in News
  • Interferon Needed for Cells to “Remember” How to Defeat a Virus
    Scientists at UT Southwestern Medical Center have determined that the immune-system protein interferon plays a key role in “teaching” the immune system how to fight off repeated infections of the same virus.The findings, available online and in the Dec. 15 issue ...More
    December 3, 2008 Posted in News
  • Scientists Find Key to Keeping Killer T Cells in Prime Shape for Fighting Infection, Cancer
    Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body’s killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and ...More
    December 2, 2008 Posted in News
  • Researchers Develop New Strategy for Broad-Spectrum Antiviral Drugs
    Bavituximab, an antiviral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents. In a study appearing in the December issue of Nature Medicine, groups of guinea pigs ...More
    November 24, 2008 Posted in News
  • Persistent Bacterial Infection Exploits Killing Machinery of Immune Cells
    A new study reveals an important and newly discovered pathway used by disease-causing bacteria to evade the host immune system and survive and grow within the very cells meant to destroy them. This discovery may lead to new treatments and vaccines for tuberculosis (TB) and ...More
    November 3, 2008 Posted in News
  • How HIV Vaccine Might Have Increased Odds of Infection
    In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection. A new study by a team of researchers at the Montpellier Institute of Molecular Genetics in France shows how ...More
    November 3, 2008 Posted in News
  • Gene Against Bacterial Attack is Unraveled
    Dutch researcher and physician Joost Wiersinga from AMC Medical Centre in Amsterdam has unraveled a genetic defense mechanism against the lethal bacteria Burkholderia pseudomallei. The research is the next step toward a vaccine against this bacterium suitable for ...More
    October 28, 2008 Posted in News