Macrophages


  • War Between Bacteria and Phages Benefits Humans
    In the battle between our immune systems and cholera bacteria, humans may have an unknown ally in bacteria-killing viruses known as phages. In a new study, researchers from Tufts University, Massachusetts General Hospital, Partners In Health, Haiti's National Public Health ...More
    4 weeks ago Posted in News
  • OTC Pain Reliever May Restore Immune Function in Old Age
    New research involving mice suggests that the key to more youthful immune function might already be in your medicine cabinet. In a report published in the Journal of Leukocyte Biology scientists show that macrophages from the lungs of old mice had different responses to ...More
    4 weeks ago Posted in News
  • Insights Into How TB Tricks the Immune System Could Help Combat the Disease
    Researchers have identified a potential way to manipulate the immune system to improve its ability to fight off tuberculosis (TB). TB is a major problem for both humans and cattle and the new findings could help scientists to create better drugs to combat the disease in ...More
    October 23, 2013 Posted in News
  • TB and Parkinson's Disease Linked by Unique Protein
    A protein at the center of Parkinson’s disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to scientists led by UC San Francisco microbiologist and tuberculosis expert Jeffery Cox, PhD. The ...More
    September 5, 2013 Posted in News
  • Study Finds Depletion of Alveolar Macrophages Linked to Bacterial Super-Infections
    A recent study published in the July issue of the Journal of Immunology helps explain why some humans contract bacterial super-infections like pneumonia with influenza. The research was led by Le Bonheur pediatrician-in-chief Jon McCullers, MD, an infectious disease ...More
    July 22, 2013 Posted in News
  • Scientists Weaken HIV Infection in Immune Cells Using Synthetic Agents
    HIV is notorious for hiding within certain types of cells, where it reproduces at a slowed rate and eventually gives rise to chronic inflammation, despite drug therapy. But researchers at Temple University School of Medicine's Department of Pathology and Laboratory Medicine ...More
    May 2, 2013 Posted in News
  • New Antibiotic is Based on Studies of Phage
    A new broad-spectrum antibiotic, developed jointly by scientists at the Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus bacteria that do not respond to traditional drugs. The ...More
    April 11, 2013 Posted in News
  • Immune Cell Suicide Alarm Helps Destroy Escaping Bacteria
    Cells in the immune system called macrophages normally engulf and kill intruding bacteria, holding them inside a membrane-bound bag called a vacuole, where they kill and digest them. ...More
    January 28, 2013 Posted in News
  • Same Conditions, Different Outcome in Fungal Infection
    Cryptococcus neoformans is a life-threatening human fungal pathogen that is responsible for an estimated 1 million cases of meningitis each year, primarily in HIV-infected and other immunocompromised patients. Interaction with immune cells called macrophages is a key step ...More
    September 1, 2011 Posted in News, Infections & Pathogens
  • How Q Fever Invades and Replicates Inside Killer Immune Cells
    As part of its life cycle Coxiella burnetii, the bacterial pathogen responsible for Q fever, replicates inside a membrane-bound compartment or "parasitophorous vacuole" (PV) within immune cells. The organism manipulates macrophages to create the PV as well as optimal ...More
    September 1, 2011 Posted in News, Infections & Pathogens
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