Mycobacterium Tuberculosis

  • TB Bacterium's Outer Cell Wall Blocks Key Part of the Body's Defense
    The bacterium that causes tuberculosis has a unique molecule on its outer cell surface that blocks a key part of the body’s defense. New research suggests this represents a novel mechanism in the microbe’s evolving efforts to remain hidden from the human immune system. ...More
    October 3, 2011
    Posted in News, Infections & Pathogens
  • TB Discovery Paves the Way for Drugs that Prevent Lung Destruction
    Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis (TB), they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning that the finding could lead quickly to new ...More
    April 25, 2011
    Posted in News
  • Efficacy of TB Vaccine is Enhanced
    Nele Festjens and Nico Callewaert of VIB and Ghent University have improved the efficacy of the vaccine for tuberculosis. The new vaccine affords -- as already proven in mice -- better protection against the disease. The development of a new tuberculosis vaccine is a ...More
    February 18, 2011
    Posted in News
  • Multi-Tasking Protein Provides New Approaches for Anti-Tuberculosis Drugs
    In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes ...More
    February 15, 2011
    Posted in News
  • New Tool in the Fight Against Tuberculosis
    Researchers at the Institute for Genomic Biology at the University of Illinois have developed a way to harness the prodigious quantities of both genomic and metabolic data being generated with high-throughput genomics and other techniques. They have developed an algorithm ...More
    October 7, 2010
    Posted in News
  • Scientist Awarded $4 Million to Develop Genetic Strategy to Combat TB
    William R. Jacobs, Jr., PhD, professor of microbiology and immunology and of genetics at Albert Einstein College of Medicine of Yeshiva University, who is also a Howard Hughes Medical Institute (HHMI) investigator, has been awarded a three-year, $4 million grant from the ...More
    October 4, 2010
    Posted in News
  • Virginia Tech Professor Discovers New TB Pathogen
    Kathleen Alexander, associate professor of wildlife in Virginia Tech's College of Natural Resources and Environment, has discovered a novel tuberculosis (TB) species in the Mycobacterium tuberculosis complex, a group of pathogens that have adapted by using mammals as hosts. ...More
    September 30, 2010
    Posted in News
  • Study Finds Possible 'Persistence Switch' for Tuberculosis
    An examination of a portion of the tuberculosis genome that responds to stress has allowed Rice University bioengineers Oleg Igoshin and Abhinav Tiwari to zero in on a network of genes that may "switch" the disease into dormancy. The bacteria that cause tuberculosis (TB), ...More
    September 17, 2010
    Posted in News
  • New Dual Recognition Mechanism Discovered in Tuberculosis
    One third of the world's population is infected with Mycobacterium tuberculosis (MTB), which leads to tuberculosis (TB), a leading cause of death world-wide. A new discovery, led by a team of researchers from Case Western Reserve University School of Medicine, offers hope ...More
    September 10, 2010
    Posted in News
  • Breathalyzer Detection of TB Antigen
    Researchers describe a novel device that utilizes immunosensor and bio-optical technology to detect M. tuberculosis antigen (Ag85B) in cough and demonstrate its use under field conditions during a pilot study in an area of high TB incidence. ...More
    July 30, 2010
    Posted in News
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