• Medicinal Toothbrush Tree Yields Antibiotic to Treat TB in New Way
    A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way. Tuberculosis causes more deaths worldwide than any other bacterial disease. At the same time as rates are increasing, resistance strains are emerging ...More
    January 14, 2013 Posted in News
  • Researchers Find Molecule That Polices TB Lung Infection
    The presence of a certain molecule allows the immune system to effectively police tuberculosis (TB) of the lungs and prevent it from turning into an active and deadly infection, according to a new study led by researchers at Children's Hospital of Pittsburgh of UPMC and the ...More
    January 3, 2013 Posted in News
  • FDA Approves First Drug to Treat Multidrug-Resistant Tuberculosis
    The Food and Drug Administration (FDA) has approved Sirturo (bedaquiline) as part of combination therapy to treat adults with multi-drug resistant pulmonary tuberculosis (TB) when other alternatives are not available. TB is an infection caused by Mycobacterium tuberculosis ...More
    January 1, 2013 Posted in News
  • Stroke Drug Kills Bacteria That Cause Ulcers and Tuberculosis
    A drug currently being used to treat ischemic strokes may prove to be a significant advance in the treatment of tuberculosis and ulcers. In a new research report appearing online in the FASEB Journal, a compound called ebselen effectively inhibits the thioredoxin reductase ...More
    December 25, 2012 Posted in News
  • UNITAID Grants Focus on Childhood HIV/AIDS, Malaria and Tuberculosis
    UNITAID announces it has made new grants to allow hundreds of thousands of children in developing countries to access better and more affordable medicines for HIV/AIDS, malaria and tuberculosis (TB). “For too long now, the global health community has done too little to meet ...More
    December 10, 2012 Posted in News
  • SLU's TB Vaccine Research Could Accelerate Life-Saving Discoveries
    A pilot study at Saint Louis University Center for Vaccine Development could shape the future of tuberculosis vaccine research by developing tests to identify the most promising vaccine candidates to address this global health crisis. ...More
    November 28, 2012 Posted in News
  • 'Repurposed' Anti-Parasite Drug Shows Promise as New TB Treatment
    A well-established family of drugs used to treat parasitic diseases is showing surprising potential as a therapy for tuberculosis (TB), according to new research from University of British Columbia microbiologists. The findings, published online this week in the journal ...More
    November 26, 2012 Posted in News
  • 'Missing Link' Discovered in the Defense Mechanism of the Tuberculosis Pathogen
    Flemish biologists led by Joris Messens of the Flanders Institute for Biotechnology have discovered that Mycobacterium tuberculosis – the bacterium that causes tuberculosis – has an ingenious defense mechanism against oxygen. This knowledge is important in the search for a ...More
    November 14, 2012 Posted in News
  • Researchers "Watch" Antibiotics Attack Tuberculosis Bacteria Inside Cells
    Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes. As a ...More
    November 2, 2012 Posted in News
  • Structure for Promising Tuberculosis Drug Target is Discovered
    Researchers at Johns Hopkins have figured out the three-dimensional shape of the protein responsible for creating unique bonds within the cell wall of the bacteria that cause tuberculosis. The bonds make the bacteria resistant to currently available drug therapies, ...More
    October 26, 2012 Posted in News