• Researchers Untangle Genetics of Drug-Resistant TB
    For years, physicians around the world have watched as strain after strain of the deadly bacteria Mycobacterium tuberculosis evolves resistance to drugs. Over the last few decades researchers have used the tools of molecular biology to identify a handful of individual ...More
    September 4, 2013 Posted in News
  • Origins of Mycobacterium tuberculosis Discovered
    Tuberculosis (TB) remains one of deadliest infectious diseases of humans, killing 50 percent of individuals when left untreated. Even today, TB causes up to 2 million deaths every year mainly in developing countries. Multidrug-resistance is a growing threat in the fight ...More
    September 4, 2013 Posted in News
  • Adding Blood Pressure Drug to Standard Antibiotics Speeds up TB Treatment
    Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in ...More
    August 29, 2013 Posted in News
  • Microneedle Patch Could Replace Standard Tuberculosis Skin Test
    Each year, millions of people in the United States get a tuberculosis skin test to see if they have the infection that still affects one third of the world’s population. But the standard diagnostic test is difficult to give, because a hypodermic needle must be inserted at a ...More
    August 26, 2013 Posted in News
  • Tuberculosis Genomes Reveal Secrets of Pathogen's Success
    By any measure, tuberculosis (TB) is a wildly successful pathogen. It infects as many as 2 billion people in every corner of the world, with a new infection of a human host estimated to occur every second. Now, thanks to a new analysis of dozens of tuberculosis genomes ...More
    August 21, 2013 Posted in News
  • New Strategy Tests for Dangerous Stage of Tuberculosis in Asia
    More than 20,000 people in Pakistan are being tested for the potentially deadly stage of tuberculosis using a new strategy developed at UC Davis Health System to effectively detect the disease in children for the first time. At least 600 million people in Pakistan, India ...More
    August 21, 2013 Posted in News
  • Preventive Antibiotics for Tuberculosis Reduce Deaths Among People with HIV Disease
    As part of the largest international research effort ever made to combat tuberculosis, a team of Johns Hopkins and Brazilian experts has found that preventive antibiotic therapy for people with HIV lowers this group’s chances of developing TB or dying. Specifically, they ...More
    August 16, 2013 Posted in News
  • New Hope for Improved TB Treatments
    Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments. Published online in the Journal of Infectious Diseases, the study investigated the proteins that are ...More
    August 9, 2013 Posted in News
  • Study Explains Why Africans May be More Susceptible to Tuberculosis
    A researcher from the Perelman School of Medicine at the University of Pennsylvania and colleagues have identified the genetic mutation in Africans with HIV that puts them at a much higher risk for tuberculosis (TB) infections. Africans have some of the highest rates of TB ...More
    July 26, 2013 Posted in News
  • FDA Permits Marketing of Xpert MTB/RIF Assay
    The Food and Drug Administration (FDA) today allowed marketing of the Xpert MTB/RIF Assay, the first FDA-reviewed test that can simultaneously detect bacteria that cause tuberculosis (TB) and determine if the bacteria contain genetic markers that makes them resistant to ...More
    July 26, 2013 Posted in News