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Tuberculosis


  • Directly Observed Therapy for Multidrug-Resistant TB Decreases Mortality
    Directly observed therapy (DOT) for multidrug-resistant tuberculosis (MDR TB) was associated with a 77 percent decrease in mortality in the United States, compared to self-administered therapy from 1993 to 2013, according to new research presented at the ATS 2017 ...More
    2 days ago Posted in News
  • TB Bacteria Evolve at an Alarming Rate
    Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology (MIPT) have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis. These genes ...More
    2 weeks ago Posted in News
  • A Defense Mechanism That Can Trap and Kill TB Bacteria
    A natural mechanism by which our cells kill the bacterium responsible for tuberculosis (TB) has been discovered by scientists at the Francis Crick Institute, which could help in the battle against antibiotic-resistant bacteria. The findings, published in Cell Host & ...More
    2 weeks ago Posted in News
  • Methods for Detecting Latent TB Need Further Studies
    Timely and accurate identification of people with latent tuberculosis infection (LTBI) is important for controlling Mycobacterium tuberculosis (TB). There is no gold standard for diagnosis of LTBI. Screening tests such as interferon gamma release assays (IGRAs) and ...More
    2 weeks ago Posted in News
  • Rutgers Researchers Determine Structure of TB Drug Target
    Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant ...More
    April 6, 2017 Posted in News
  • LSTM Reports on a New Way of Screening Potential TB Treatments
    Scientists from Liverpool School of Tropical Medicine (LSTM)'s Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for tuberculosis (TB) which may assist in the ...More
    March 29, 2017 Posted in News
  • WHO Issues Ethics Guidance to Protect the Rights of TB Patients
    New tuberculosis (TB) ethics guidance, issued today by the World Health Organization (WHO), aims to help ensure that countries implementing the End TB Strategy adhere to sound ethical standards to protect the rights of all those affected. TB, the world’s top ...More
    March 23, 2017 Posted in News
  • Global Rise of Multidrug-Resistant Tuberculosis Threatens to Derail Decades of Progress
    The rise of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) threatens to derail decades of progress in controlling the disease, according to a new report in The Lancet Respiratory Medicine published on World TB Day (March 24). Although a ...More
    March 23, 2017 Posted in News
  • TB/HIV Co-infections Up 40 Percent Across Europe Over the Last Five Years
    New data released today by the European Centre for Disease Prevention and Control (ECDC) and the WHO Regional Office for Europe ahead of World TB Day show that new tuberculosis (TB) cases and deaths in the 53 countries of the WHO European Region declined each year by 4.3 ...More
    March 20, 2017 Posted in News
  • Old Target, New Mechanism for Overcoming Tuberculosis Resistance
    In strains of tuberculosis that have developed drug resistance mutations, researchers have identified a secondary pathway that can be activated to reinstate drug sensitivity. The rise of drug-resistant tuberculosis poses a serious threat to humans, with approximately ...More
    March 16, 2017 Posted in News
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