"The company's pursuit of a safe smallpox vaccine for people around the globe has achieved extraordinary strides over the past year," said Peter Wulff, president and CEO of Bavarian Nordic. "Our groundbreaking MVA smallpox vaccine is seen by many scientific and health policy experts as a safe, effective alternative to the traditional -- or second-generation -- smallpox vaccines currently stockpiled by world governments."
According to the
Bavarian Nordic's MVA smallpox vaccine, known as IMVAMUNE, is a weakened, non-replicating form of the virus. It is currently undergoing clinical trials with the U.S. Food and Drug Administration (FDA) to be confirmed as a safe smallpox vaccine. The company's global clinical development program has already generated data on the safety of IMVAMUNE in persons with HIV as well as optimal dosing for the vaccine while an ongoing trial is investigating IMVAMUNE in persons with atopic disorders, such as eczema.
Earlier this year, the FDA also awarded IMVAMUNE its first-ever "fast track" status to a smallpox vaccine -- a designation that is intended to facilitate the development and expedite the review of new therapies targeted at treating serious and life-threatening conditions.
Taking into account the significant health risks associated with the current vaccine stockpile in 2002 the
"While Bavarian Nordic will continue to take the lead in the development of IMVAMUNE under the NIAID program, we will closely collaborate with our commercial partner GlaxoSmithKline in pursuing future government programs, including the forthcoming Request for Proposal III," added Wulff. RFP-III will outline the
* The award of RFP-II has been funded in full or in part with federal funds from the National Institute of Allergy and Infectious Diseases, the National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN266200400072C, ADB Contract No. 1-AI-40072.
Source: Bavarian Nordic