Antibiotics are a lifesaver—except when they stop working—and, unfortunately, that is happening more often as multidrug resistant bacteria render many previously useful antimicrobials ineffective.
Antibiotics & Antimicrobials
Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. Researchers have used this knowledge to help solve the X-ray crystal structure of the enzyme that makes obafluorin -- a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria.
McMaster University researchers have developed a novel new gel made entirely from bacteria-killing viruses. The anti-bacterial gel, which can be targeted to attack specific forms of bacteria, holds promise for numerous beneficial applications in medicine and environmental protection.
McMaster University researchers have developed a novel new gel made entirely from bacteria-killing viruses.
A UCLA-led research team has found that giving mice antibiotics for 10 days prior to a liver transplant leads to better liver function after the surgery.
Microbial resistance to classical antibiotics and its rapid progression have raised serious concern in the treatment of infectious diseases. Recently, many studies have been directed toward finding promising solutions to overcome these problems. Phytochemicals have exerted potential antibacterial activities against sensitive and resistant pathogens via different mechanisms of action.
A simple finger-prick blood test could help prevent unnecessary prescribing of antibiotics for people with the lung condition chronic obstructive pulmonary disease (COPD), according to a new study by researchers from Cardiff University, University of Oxford and King's College London.
Antibiotic stewardship interventions for acute respiratory infection (ARI) is feasible and effective and can significantly reduce overuse in the emergency department (ED) and urgent care center (UCC) settings.
Tooth decay is among the costliest and most widespread bacterial diseases. Virulent bacteria cause the acidification of tooth enamel and dentin, which, in turn, causes secondary tooth decay.
A million times a year, pneumonia sends American adults to the hospital. And while antibiotics help save lives, a new study shows two-thirds receive more antibiotics than they probably need.