In a research paper published today in The Lancet, an internationally recognized medical journal, researchers reported finding that a three-day course of treatment with nitazoxanide can substantially reduce the duration of severe dehydrating rotavirus diarrhea and gastroenteritis in children. The results of the research, conducted at
Worldwide, more than 1 in 40 children under the age of five are hospitalized annually because of rotavirus diarrhea. The medical and societal costs of rotavirus in the
"These findings could have worldwide impact," said Jean-Francois Rossignol, chairman and chief science officer of the Romark Institute for Medical Research.
Rossignol said the duration of rotavirus illness was reduced by almost two days in children treated with nitazoxanide, and no significant side effects were reported. "These results are encouraging and might lead us to think about new approaches to managing rotavirus disease in children," he added.
Romark presently markets nitazoxanide under the trade name Alinia, which has been approved by the Food and Drug Administration for the treatment of diarrhea in children and adults caused by Cryptosporidium or Giardia. Romark is also studying the application of nitazoxanide for the treatment of Clostridium difficile, hepatitis C and hepatitis B.
Marc Ayers, president and CEO of Romark, said the company is pursuing additional studies to have Alinia licensed for treating rotavirus gastroenteritis in children. "We are excited about the opportunity to reduce the burden of illness associated with this disease," he added.
Source: Romark Laboratories