An electronic alert system helps clinicians quickly do a bedside assessment to identify children with severe sepsis in an emergency department.
Of the nearly 1 million people in the United States who are affected by sepsis each year, almost one-fifth die. Cardiovascular complications account for approximately 80 percent of those deaths.
The Centers for Disease Control and Prevention has launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis.
With an incidence of 31.5 million worldwide and a mortality of around 17 percent, sepsis remains the most common cause of death in hospitalized patients, even in industrialized countries where antibiotics and critical care facilities are
A team of researchers from the University of Illinois and Carle Foundation Hospital in Urbana, Illinois, completed a clinical study of the device, which is the first to provide rapid, point-of-care measurement of the immune system's response, without any need to process the blood.
University of Warwick expertise is contributing to a world-first study aiming to tackle one of the biggest public health threats we face – antibiotic resistance.
Sepsis presents a major challenge for healthcare providers, especially in low-income countries where the mortality rate can exceed 60 percent. Even in advanced medical settings, sepsis is still very dangerous and accounts for over 400,000 deaths annually in the U.S. alone. While new drugs are in development, a group of researchers has determined that a combination of intravenous vitamin C, corticosteroids (a steroid), and thiamine (vitamin B) may be effective in preventing progressive organ dysfunction and reducing the number of deaths from severe sepsis and septic shock. Their findings are published in the June issue of CHEST.
An electronic sepsis alert using a combination of vital signs, risk factors and physician judgment to identify children in a pediatric emergency department with severe sepsis reduced missed diagnoses by 76 percent. The results of the study, along with an accompanying editorial, were published online Friday in Annals of Emergency Medicine ("Improving Recognition of Pediatric Severe Sepsis in the Emergency Department: Contributions of a Vital Sign-Based Electronic Alert and Bedside Clinician Identification" and "Between the Devil and the Deep Blue Sea: Use of Real-Time Tools to Identify Children with Severe Sepsis in the Pediatric Emergency Department").