Developing Vaccines for Insect-Borne Viruses
January 16th 2015Vaccines developed using proteins rather than live viruses can help protect animals and subsequently humans from insect-borne viruses, according to Alan Young, chief scientific officer for Medgene Labs, an animal health company that develops therapeutics and diagnostics, including vaccines.
Long-Acting Drug Effectively Prevents HIV-Like Infection in Primate Model
January 15th 2015A regime of anti-HIV drugs -- components of regimens to treat established HIV infection -- has the potential to protect against infection in the first place. But real life can interfere; the effectiveness of this prophylactic approach declines if the medications aren't taken as prescribed.
Iron Overload Disease Causes Rapid Growth of Potentially Deadly Bacteria, UCLA Study Finds
January 14th 2015Every summer, the news reports on a bacterium called Vibrio vulnificus found in warm saltwater that causes people to get sick, or die, after they eat raw tainted shellfish or when an open wound comes in contact with seawater. People with a weakened immune system, chronic liver disease or iron overload disease are most at risk for severe illness. Vibrio vulnificus infections in high-risk individuals are fatal 50 percent of the time. Now, researchers at UCLA have figured out why those with iron overload disease are so vulnerable. People with the common genetic iron overload disease called hereditary hemochromatosis have a deficiency of the iron-regulating hormone hepcidin and thus develop excess iron in their blood and tissue, providing prime growth conditions for Vibrio vulnificus.
New Model Predicts Ebola Epidemic in Liberia Could End by June
January 14th 2015The Ebola epidemic in Liberia could likely be eliminated by June if the current high rate of hospitalization and vigilance can be maintained, according to a new model developed by ecologists at the University of Georgia and Pennsylvania State University.