Current guidelines to help prevent bloodstream infections during intravenous feeding may need revisions to strengthen protections for patients, a new study finds. Researchers at the United Kingdom's University of Southampton found that current guidelines do not account for other independent factors that can affect the growth of potentially deadly microorganisms. Their study was published today in the OnlineFirst version of the Journal of Parenteral and Enteral Nutrition (JPEN), the research journal of the American Society for Parenteral and Enteral Nutrition (ASPEN).
Existing guidelines restrict how long a single bag of parenteral nutrition (PN) containing lipids can be used due to the ability of lipids to encourage the growth of microorganisms. This study looked at the growth of Escherichia coli (E. coli) and Enterococcus durans (E. durans) in PN to see if other factors can affect microbial growth.
The study found that additional factors, including glucose concentration, proportion of glucose to lipid, and osmolarity (concentration of a solution that can pass through the wall of a living cell through osmosis), can affect microbial growth apart from the presence of lipids.
The study's researchers recommend that these additional factors should be considered when making clinical and policy decisions to limit the potential growth of microorganisms in PN.
Source: American Society for Parenteral and Enteral Nutrition (ASPEN)
Beyond the Surface: Rethinking Environmental Hygiene Validation at Exchange25
June 30th 2025Environmental hygiene is about more than just shiny surfaces. At Exchange25, infection prevention experts urged the field to look deeper, rethink blame, and validate cleaning efforts across the entire care environment, not just EVS tasks.
A Controversial Reboot: New Vaccine Panel Faces Scrutiny, Support, and Sharp Divides
June 26th 2025As the newly appointed Advisory Committee on Immunization Practices (ACIP) met for the first time under sweeping changes by HHS Secretary Robert F. Kennedy Jr, the national spotlight turned to the panel’s legitimacy, vaccine guidance, and whether science or ideology would steer public health policy in a polarized era.
Getting Down and Dirty With PPE: Presentations at HSPA by Jill Holdsworth and Katie Belski
June 26th 2025In the heart of the hospital, decontamination technicians tackle one of health care’s dirtiest—and most vital—jobs. At HSPA 2025, 6 packed workshops led by experts Jill Holdsworth and Katie Belski spotlighted the crucial, often-overlooked art of PPE removal. The message was clear: proper doffing saves lives, starting with your own.