PITTSBURGH -- The University of Pittsburgh has been awarded $18 million from the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, for the construction of a Regional Biocontainment Laboratory (RBL), a biosafety facility dedicated to research on agents that cause naturally occurring and emerging infections, as well as potential agents of bioterrorism. The University of Pittsburgh RBL will be housed in the Biomedical Science Tower 3; construction of the RBL is scheduled to be completed by the summer of 2005.
"The construction of a high-level biosafety facility will contribute to the University of Pittsburgh's growing state-of-the-art biodefense program by creating a dedicated site where this essential research can be conducted safely," said Arthur S. Levine, MD, senior vice chancellor for the health sciences and dean of the School of Medicine at the University of Pittsburgh as well as principle investigator on this grant. "This facility, in concert with existing resources at the University of Pittsburgh, will enable us to greatly accelerate the development of vaccines, drugs and diagnostics for viruses and other infectious agents."
In addition to providing matching funds for the RBL, the University of Pittsburgh, which currently ranks eighth in the nation in research support from the NIH, plans on developing a vaccine program focusing on basic and translational research on naturally occurring diseases like SARS, West Nile Virus, dengue, hemorrhagic viruses and encephalitis viruses. These diseases cause great morbidity and mortality in developing countries, and in some cases can cause infection in the United States. Creating vaccines for these diseases is of special interest as they not only affect people naturally, but they also have a great potential to be "weaponized."
Immunology and infectious disease have been and continue to be research priorities at the University of Pittsburgh. Over the years, researchers have built world-class federally funded programs; these programs will both benefit from and contribute to the RBL. The RBL will also benefit from access to the extensive network of urban and rural hospitals of the University of Pittsburgh Medical Center.
"We live in an age when it is critical that we use the nation's extraordinary scientific talent in the pursuit of answers to the global security threats posed by infectious diseases," said Tara O'Toole, chief executive officer at the Center for Biosecurity, University of Pittsburgh Medical Center. "This new laboratory will enable University of Pittsburgh medical researchers to delve further into possible treatments and to develop vaccines against diseases that might result from bioterrorist attack or from natural outbreaks."
The NIAID offered funding for nine RBLs and two National Biocontainment Laboratories (NBLs) based on recommendations from an expert panel that cited the nation's deficit of biosafety laboratories as a significant barrier to progress in biodefense research. The NBL and RBL programs provide funding for the design and construction of comprehensive, state-of-the art biosafety laboratories (BSL) and associated research and administrative support space. The BSL labs will be designed and built using the strictest federal standards, incorporating special engineering and design features to prevent microorganisms from being released into the environment. Numerous safety and decontamination features will provide multiple layers of protection for lab workers and the surrounding environment. The labs will be available and prepared to assist national, state and local public health efforts in the event of a bioterrorism or infectious disease emergency.
Source: University of Pittsburgh
The Next Frontier in Infection Control: AI-Driven Operating Rooms
Published: July 15th 2025 | Updated: July 15th 2025Discover how AI-powered sensors, smart surveillance, and advanced analytics are revolutionizing infection prevention in the OR. Herman DeBoard, PhD, discusses how these technologies safeguard sterile fields, reduce SSIs, and help hospitals balance operational efficiency with patient safety.
Targeting Uncertainty: Why Pregnancy May Be the Best Time to Build Vaccine Confidence
July 15th 2025New national survey data reveal high uncertainty among pregnant individuals—especially first-time parents—about vaccinating their future children, underscoring the value of proactive engagement to strengthen infection prevention.
CDC Urges Vigilance: New Recommendations for Monitoring and Testing H5N1 Exposures
July 11th 2025With avian influenza A(H5N1) infections surfacing in both animals and humans, the CDC has issued updated guidance calling for aggressive monitoring and targeted testing to contain the virus and protect public health.
IP LifeLine: Layoffs and the Evolving Job Market Landscape for Infection Preventionists
July 11th 2025Infection preventionists, once hailed as indispensable during the pandemic, now face a sobering reality: budget pressures, hiring freezes, and layoffs are reshaping the field, leaving many IPs worried about their future and questioning their value within health care organizations.