News

An interdisciplinary team of scientists and engineers at Vanderbilt University headed by Stevenson Professor of Chemistry David Wright has designed a new kind of rapid diagnostic test for malaria that has received a $100,000 Grand Challenges Explorations grant which is designed to support innovative global health and development research projects. It is one of 56 such grants announced today by the Bill & Melinda Gates Foundation.

Scientists at the Gladstone Institutes discovered that the vaginal immune system is suppressed in response to RNA viruses, such as Zika. The delayed antiviral immune response allows the virus to remain undetected in the vagina, which can increase the risk of fetal infection during pregnancy.

Most antibiotics in use today are based on natural molecules produced by bacteria--and given the rise of antibiotic resistance, there's an urgent need to find more of them. Yet coaxing bacteria to produce new antibiotics is a tricky proposition. Most bacteria won't grow in the lab. And even when they do, most of the genes that cause them to churn out molecules with antibiotic properties never get switched on.

Researchers at the National Institutes of Health’s National Center for Advancing Translational Sciences (NCATS), Clinical Center and National Institute of Allergy and Infectious Diseases (NIAID) have created a new way to identify drugs and drug combinations that may potentially be useful in combating infections that are resistant to many different antibiotics. They developed an assay (test) to rapidly screen thousands of drugs to determine how effective they were against a variety of types of resistant bacteria.