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It’s usually the small things that are overlooked, emphasizes John Lowe, PhD, assistant professor in the Department of Environmental, Agricultural and Occupational Health at University of Nebraska Medical Center (UNMC). Lowe’s facility was among a handful in the United States that treated patients infected with Ebola virus in 2014. Healthcare systems such as UNMC and Emory University Hospital in Atlanta have well-established biocontainment units and expert staff that helped stop the spread of the deadly pandemic pathogen.

Many viral infections, such as the common cold, cause mild illnesses that the body’s immune system eventually defeats. But when viruses cause severe disease, doctors have few options for effective treatment. Studying mice with a variety of viral infections, scientists at Washington University School of Medicine in St. Louis have demonstrated a way to dial up the body’s innate immune defenses while simultaneously attacking a protein that many viruses rely on to replicate.