CDC Lab Determines Possible Staff Exposure to Anthrax

The Centers for Disease Control and Prevention (CDC) announced today that approximately 75 Atlanta-based staff are being monitored or provided antibiotics because they may have been unintentionally exposed to live Bacillus anthracis (anthrax) after established safety practices were not followed.

Out of an abundance of caution, the CDC says it is taking aggressive steps to protect the health of all involved, including providing protective courses of antibiotics for potentially exposed staff. Based on most of the potential exposure scenarios, the risk of infection is very low. Based on the review to date, the CDC says it believes that other CDC staff, family members, and the general public are not at risk of exposure and do not need to take any protective action. Although the investigation continues, early reports show that one of its Roybal campus biosafety level 3 (BSL3) labs was preparing B. anthracis samples for research in other CDC labs at lower biosafety levels to yield new means of detecting dangerous pathogens in environmental samples. However, the lab used a procedure that did not adequately inactivate the samples.

The potentially infectious samples were moved and used for experimentation in three CDC Roybal campus laboratories not equipped to handle live B. anthracis.  Workers, believing the samples were inactivated, were not wearing adequate personal protective equipment while handling the material.

Lab safety investigators also determined that, sometime between June 6 and June 13, procedures used in two of the three labs may have aerosolized the spores. Environmental sampling was done, lab and hallway areas were decontaminated and laboratories will be re-opened when safe to operate.

The unintentional exposure was discovered June 13 when the original bacterial plates were gathered for disposal and B. anthracis colonies (live bacteria) were found on the plates. These plates had appeared negative for B. anthracis at the time samples were distributed to the other CDC laboratories.  The review began immediately to assess the health risk, and those workers handling the plates were immediately notified.

The CDC’s guiding principles for laboratory work are to ensure the safety of all staff and the community and be as transparent as possible about our work as staff conduct high-quality scientific research to protect people in this country and around the world.

The CDC says it is continuing its internal review to determine why validated procedures were not used by the lab. Also, the CDC has reported the incident to the Federal Select Agent Program. Given that CDC expert protocols were not followed, disciplinary action(s) will be taken as necessary. In addition, the CDC will review the safety protocol again with all employees who work in this area.

Source: CDC