The incidence of vancomycin-resistant enterococci (VRE) remains sporadic in Switzerland. Researchers in Lausanne, Switzerland report an unprecedented VRE outbreak in a 900-bed tertiary care hospital and describe its molecular epidemiology. VRE was detected in clinical specimens by standard procedures. Carriage screening was performed by rectal swab. Swabs were inoculated into an enrichment broth and grown on chromogenic VRE agar. Isolates were typed by PFGE.
Senn, et al. report that in November 2010, a first case of VRE was detected in a urine culture. The investigation identified three secondary cases in roommates (asymptomatic carriage). A second clinical case was detected in January 2011. Four secondary cases were identified. Both index cases were previously hospitalized in the same regional hospital. All patients transferred from the regional hospital were screened for VRE. In addition, weekly screening was initiated in patients hospitalized in the epidemic ward.
In total, from November 2010 to March 2011, 31 VRE cases were identified: four in clinical specimens (two urine and two wound) and 27 in screening swabs. One patient presented a VRE bacteremia. Molecular analysis showed that all isolates except two had the same PFGE pattern. The 2 different strains had only a variation of one to two bands and were probably related to the outbreak. Infection control measures (contact isolation of carriers and roommates, quarantine of the epidemic ward and reinforcement of environment disinfection) were implemented.
The researchers emphasize that the VRE outbreak was controlled by implementation of strict infection control measures.
Reference: L Senn, C Petignat, G Prod'hom, G Greub, P Basset, DS Blanc and G Zanetti. Unprecedented nosocomial spread of vancomycin-resistant Enterococcus faecium in a tertiary-care hospital in Switzerland. Presentation at the International Conference on Prevention & Infection Control (ICPIC). BMC Proceedings 2011, 5(Suppl 6):P22doi:10.1186/1753-6561-5-S6-P22
Long COVID: Urgent Findings, Including Brain Alterations, Call for Renewed Public Health Focus
October 21st 2024New research highlights long COVID’s global impact, cognitive decline, and societal consequences, urging renewed focus on prevention, including vaccination, mask use, and better air quality.
Strengthening Defenses: Integrating Infection Control With Antimicrobial Stewardship
October 11th 2024Use this handout to explain the basics of why infection prevention and control and antimicrobial stewardship are essential and how the 2 fields must have a unified approach to patient and staff safety
NP and PA-Led Practices: A Possible Remedy for Health Care Worker Burnout
October 8th 2024Nurse practitioner (NP) and Physician Assistant (PA)-led practices offer autonomy, flexible schedules, and smaller patient loads, which could help mitigate burnout while reducing pressure on traditional healthcare systems and improving infection prevention.
Barrier Against Infection: Importance and Challenges of Isolation Room Cleaning in Hospitals
October 4th 2024Isolation rooms are essential for infection control in health care, relying on specialized design, advanced cleaning protocols, and technology to prevent cross-contamination and safeguard patient safety.