Clinical Interventions

October 2019 Bug of the Month

September 25, 2019

Bug of the Month helps educate readers about existing and emerging pathogens of clinical importance in healthcare facilities today.

NIH and Partners to Launch HIV Vaccine Efficacy Trial in the Americas and Europe

August 27, 2019

The National Institutes of Health and partners today announced plans to conduct a Phase 3 HIV vaccine efficacy trial at multiple clinical research sites in North America, South America and Europe. The trial, called HPX3002/HVTN 706 or Mosaico, will assess whether an investigational vaccine regimen designed to induce immune responses against a variety of global HIV strains can safely and effectively prevent HIV acquisition among men who have sex with men and transgender people.

Enzyme Drives New Class of Antibiotics

July 31, 2019

Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. Researchers have used this knowledge to help solve the X-ray crystal structure of the enzyme that makes obafluorin -- a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria.

Big-data Analysis Shows No Correlation Between Vaccinations and MS

July 31, 2019

Data from more than 12,000 multiple sclerosis (MS) patients formed the basis of a study by the Technical University of Munich (TUM) which investigated the population's vaccination behavior in relation to MS. It showed that five years before their diagnosis, MS patients were statistically less likely to receive vaccinations than comparator groups. Consequently, there was no positive correlation between vaccinations and the development of MS.

New Portable Device Lets Smartphones Count Real Biological Viruses

July 30, 2019

The current leading method to assess the presence of viruses and other biological markers of disease is effective but large and expensive. It is prohibitively difficult for use in many situations, especially due to certain economic and geographic factors.

Bacteria-Killing Gel Heals Itself While Healing You

July 25, 2019

McMaster University researchers have developed a novel new gel made entirely from bacteria-killing viruses. The anti-bacterial gel, which can be targeted to attack specific forms of bacteria, holds promise for numerous beneficial applications in medicine and environmental protection.

Researchers Develop Novel Vaccine That Induces Antibodies That Contribute to Protection

July 23, 2019

Researchers at the Icahn School of Medicine at Mount Sinai have developed a novel vaccine consisting of DNA and recombinant proteins composed of a portion of an HIV protein and another unrelated protein. This vaccine was tested in monkeys and was shown to induce antibodies similar to those associated with protection from HIV, the virus that causes AIDS.

Evaluation of the Complexity of Indoor Air in Hospital Wards

July 22, 2019

The aim of this study by Ling and Hui (2019) was to establish a set of assessment methods suitable for evaluating the complex indoor environment of hospital wards and to ascertain the composition of bacteria and microbial ecology of hospital wards.

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