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The Needlestick Safety and Prevention Act became Public Law 106-430 on November 6, 2000. In 2001, in response to the Needlestick Safety and Prevention Act, OSHA revised the Bloodborne Pathogens Standard (29 CFR 1910.1030) to contain language designed to prevent needlestick injuries to healthcare workers. In 2013 publications are still full of advice on preventing needlestick injuries for healthcare workers.

Nurse-led initiatives in Indiana measurably improved patient outcomes while demonstrating anticipated financial savings of more than $5.2 million to their organizations, according to initial results from a hospital-based nurse leadership and innovation training program launched last year by the American Association of Critical-Care Nurses (AACN).