New UGA Technology Makes Textiles Permanently Germ-Free
July 5th 2011A University of Georgia (UGA) researcher has invented a new technology that can inexpensively render medical linens and clothing, face masks, paper towelsand yes, even diapers, intimate apparel and athletic wear, including smelly sockspermanently germ-free.
Joint Commission Center for Transforming Healthcare Aims to Reduce Risk of Wrong-Site Surgery
June 29th 2011Healthcare professionals and patients all agree that wrong-site surgery is a serious and preventable adverse event that should never happen. Although reporting is not mandatory in most states, some estimates put the national incidence rate, which includes wrong patient, wrong procedure, wrong site, and wrong side surgeries, as high as 40 per week. Recognizing this as a critical patient safety issue, eight U.S. hospitals and ambulatory surgical centers teamed up with the Joint Commission Center for Transforming Healthcare to address the problem. The Center and the participating organizations used methods such as Lean Six Sigma and change management to discover the causes of and put a stop to these preventable breakdowns in patient care.
Living Antibiotic is Effective Against Salmonella
June 28th 2011Scientists have tested a predatory bacterium Bdellovibrio against Salmonella in the guts of live chickens. They found that it significantly reduced the numbers of Salmonella bacteria and, importantly, showed that Bdellovibrio are safe when ingested. The research was funded by the Biotechnology and Biological Sciences Research Council, carried out by professor Liz Sockett's team at the University of Nottingham, with Dr Robert Atterbury and professor Paul Barrow at the University of Nottingham Vet School; and published in the journal Applied and Environmental Microbiology. Researcher Dr. Laura Hobley notes, "Bdellovibrio has the potential to be used as a living antibiotic against some major human and animal pathogens, such as E. coli and other Gram-negative bacteria." Previous studies have shown that Bdellovibrio is very effective at invading and killing other bacterial cells in a test tube. It looks likely to provide an alternative to antibiotic medicines at a time when bacterial resistance is a significant problem to human and animal health. Hobley adds, "We think that Bdellovibrio could be particularly useful as a topical treatment for wounds or foot rots but we wanted to know what might happen if it is ingested either deliberately as a treatment, or by accident." Salmonella likes to grow in the guts of poultry and other animals and can cause food poisoning in humans. In lab experiments Bdellovibrio can kill Salmonella by breaking into the cells and destroying them from the inside. This research shows that it also works inside the gut of a bird and is safe, not harming them or changing their behaviour. Bdellovibrio reduced the numbers of Salmonella by 90 percent and the birds remained healthy, grew well, and were generally in good condition. "We concluded that Bdellovibrio aren't long lived in the bird guts they had a strong effect for about 48 hours, which dropped off after this time. If we were to use this method to completely rid the birds of Salmonella, we might have to test a program of multiple dosing. But the point of this study was really to ensure that Bdellovibrio is safe and effective when ingested," says Hobley. Professor Douglas Kell, chief executive, BBSRC, says, "Once we have understood the fundamental nature of an extraordinary organism such as Bdellovibrio, it makes sense that we should look at potential uses for it. The impact of bacterial infections on human and animal health is significant and since antibiotic resistance is a major issue, alternatives from nature may become increasingly important."