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While many bacteria exist as aggressive pathogens, causing diseases ranging from tuberculosis and cholera, to plague, diphtheria and toxic shock syndrome, others play a less malevolent role and some are critical for human health.

The advent of combination antiretroviral therapy in 1996, and patients success using the drugs in managing HIV, led to diminished interest in research towards a cure for a number of years.

Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as autism a decade ago. Since then, studies of postmortem brains and of individuals with autism, as well as epidemiological studies, have supported the correlation between alterations in the immune system and autism spectrum disorder.

According to an Institute of Medicine (IOM) report, there are 2 million healthcare-associated infections (HAIs) per year in the United States. We also know that 100,000 of these infected patients die. The problem with this picture is that HAIs are preventable and with proper attention, these lives could be saved. Hence, our focus as infection preventionists needs to be on infection prevention rather than infection control.