LEXINGTON, Mass. -- Cubist Pharmaceuticals, Inc. today announced that it has begun shipping its flagship antibiotic product, Cubicin (daptomycin for injection), to U.S. hospitals. Cubist received U.S. Food & Drug Administration marketing approval for Cunicin on Sept. 12, 2003.
Cubicin is indicated for the treatment of complicated skin and skin structure infections (cSSSI) caused by gram-positive bacteria, including those caused by MRSA (methicillin-resistant Staphylococcus aureus) and MSSA (methicillin-susceptible S. aureus). Cubicin is currently the only once-daily rapidly bactericidal antibiotic proven effective against both MRSA and MSSA.
Cubicin is an antibacterial agent from a new class of antibiotics called cyclic lipopeptides, and has clinical utility in the treatment of infections caused by aerobic gram-positive bacteria. The in vitro spectrum of activity of Cubicin encompasses most clinically relevant gram-positive pathogenic bacteria, including bacterial isolates resistant to methicillin, vancomycin and linezolid. In the U.S., MRSA now accounts for nearly 60 percent of staphylococcal infections in hospitals, and the incidence of MRSA in the community is on the rise as well.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cubicin and other antibacterial drugs, Cubicin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Patients receiving Cubicin should be observed for the development of muscle pain or weakness and have creatine phosphokinase (CPK) levels monitored weekly. Cubicin is not indicated for the treatment of pneumonia. The most commonly reported adverse events in the cSSSI clinical trials in adults were constipation, nausea and headache.
Cubist Pharmaceuticals, Inc. is a biopharmaceutical company focused on the research, development and commercialization of anti-infective drugs.
Source: Cubist Pharmaceuticals
Endoscopes and Lumened Instruments: New Studies Highlight Persistent Contamination Risks
May 7th 2025Two new studies reveal troubling contamination in both new endoscopes and cleaned lumened surgical instruments, challenging the reliability of current reprocessing practices and manufacturer guidelines.
Happy Hand Hygiene Day! Rethinking Glove Use for Safer, Cleaner, and More Ethical Health Care
May 5th 2025Despite their protective role, gloves are often misused in health care settings—undermining hand hygiene, risking patient safety, and worsening environmental impact. Alexandra Peters, PhD, points out that this misuse deserves urgent attention, especially today, World Hand Hygiene Day.