Methicillin Resistance Among Clinical Isolates of Staphylococcus aureus in Egypt


About 40 percent to 70 percent of the infections caused by Staphylococcus aureus strains are due to methicillin-resistant ones. These isolates are usually multi-drug resistant and harder to treat endangering hundreds of thousands of patients worldwide and costing billions in added healthcare costs. Accurate numbers describing the prevalence and characteristics of these infections and the added burden they cause to developing countries in the eastern Mediterranean and African regions are lacking. Egypt is no exception. In this article that appeared in Infectious Disorders - Drug Targets, Dr. Alaa Abouelfetouh, associate professor of microbiology at Alexandria University, is gathering the published data describing methicillin resistance in S. aureus (MRSA) in Egypt.

The reports described a general MRSA prevalence rate of 50 percent to 82 percent among hospitalized patients mainly in the largest two Egyptian cities Cairo and Alexandria and a lower rate of 24 percent in Minia, an important but less populated city in southern Egypt. The articles that investigated community acquired MRSA reported 19 percent to 47 percent prevalence. Some of these studies molecularly characterized the types of the MRSA isolates using different techniques; SCCmec typing, or spa typing and multi-locus sequence typing (MLST). SCCmec types V, IV and its subtypes were detected in two separate studies. A different study revealed a MRSA prevalence rate among retail chickens of 38 percent which could act as reservoir for resistance transfer to humans.

"Although the numbers point to an increasing rate of MRSA occurrence, especially in large cities such as Cairo and Alexandria, in the absence of a national surveillance program it is not possible to extrapolate these results to cover the whole country," warns Abouelfetouh.

Despite these alarming levels of MRSA in hospital and community settings, awareness of MRSA control measures among the medical staff at one of the major health centers in Egypt was at the 67 percent level.

Source: Bentham Science Publishers

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