MRSA Linked to Livestock is Found in Hospitals, Study Finds

Article

Some MRSA bugs in UK hospitals can be traced back to a type of bacteria found in farm animals, a study suggests. A strain of drug-resistant bacteria carried by some livestock – the MRSA strain Staphylococcus aureus CC398 – has also been found in patients, researchers say.

People and animals generally harbour distinct variants of CC398, which the team say evolved from the same original bacteria. However, the CC398 strain found in livestock can be transmitted to humans, and the study shows that this has happened on many occasions.

The study provides new evidence that the livestock-associated CC398 strain could spread in hospitals, including those with newborn babies.

CC398 from farm animals is resistant to some common antibiotic drugs, which could make it harder to treat. The strain's enhanced drug resistance in livestock is likely to be the result of widespread use of antibiotics on farms, scientists say.

Patients in hospitals and nursing homes are at increased risk of MRSA infection, but healthy people in the wider community can also become infected with some strains.

Scientists at the University of Edinburgh studied how the CC398 strain evolved using a state-of-the-art genetic analysis technique. For the first time, researchers unravelled the full genetic code of CC398 strains from the UK, and compared these with published genetic data on CC398 bugs from humans and livestock around the world.

They say that CC398 has entered the UK on several occasions since the mid-1940s, though the original source of the bacteria remains unclear.

Lead researcher Dr. Melissa Ward says, "Our findings emphasise the need for strict biosecurity practices in the food production industry, as well as continued surveillance and infection control of MRSA in hospitals. Responsible use of antibiotics in healthcare settings and agriculture is of utmost importance."

The study, published in the journal Applied and Environmental Microbiology, was carried out by the University of Edinburgh's Centre for Immunity, Infection and Evolution and The Roslin Institute, in collaboration with the Scottish MRSA Reference Laboratory.

The study was funded by the European Commission Framework Programme 7, the Biotechnology and Biological Sciences Research Council, the Wellcome Trust, the Scottish Universities Life Sciences Alliance, Pfizer and the Medical Research Council.

Source: University of Edinburgh



Recent Videos
Pathogen Playbook Presenter: Sharon Ward-Fore, BS, MS, MT(ASCP), CIC, FAPIC
Mark Wiencek, PhD
Rebecca Crapanzano-Sigafoos, DrPH, CIC, AL-CIP, FAPIC
The CDC’s updated hospital respiratory reporting requirement has added new layers of responsibility for infection preventionists. Karen Jones, MPH, RN, CIC, FAPIC, clinical program manager at Wolters Kluwer, breaks down what it means and how IPs can adapt.
Studying for the CIC using a digital tablet and computer (Adobe Stock 335828989 by NIKCOA)
Infection Control Today's Conversations with the HSPA President, Arlene Bush, CRCST, CER, CIS, SME, DSMD, CRMST
Infection Control Today's Conversations with the HSPA President, Arlene Bush, CRCST, CER, CIS, SME, DSMD, CRMST
Cheron Rojo, BS, FCS, CHL,  CER, CFER, CRCST
Matthias Tschoerner, Dr Sc
Standardizing Cleaning and Disinfection
Related Content