New Agreement Will Speed Research Efforts on Microbicides for Women

Article

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announces an agreement with the International Partnership for Microbicides (IPM) to share information and expertise in an effort to develop vaginal microbicides, which are creams, gels or other substances that can be applied topically and may reduce the transmission of HIV and other sexually transmitted infections.

There is an urgent need for products, such as microbicides, that women can use to protect themselves from HIV, notes NIAID Director Anthony S. Fauci, MD. We know that women make up nearly half of all people living with HIV worldwide and that most cases of new HIV infection in women are the result of heterosexual intercourse. This new agreement draws on complementary strengths of our two organizations to speed the progress of promising microbicides through the research and development pipeline.

Adds IPM CEO Zeda Rosenberg, ScD, This agreement opens the door to a range of scientific collaborations that we hope will lead to an effective microbicide as soon as possible.

Although no licensed microbicide is currently available, large-scale effectiveness trials of five candidate microbicides are under way, including an NIAID-sponsored trial that opened in February 2005.

The agreement between NIAID and IPM includes plans for regular interaction between the scientific leadership of the two organizations, information-sharing meetings and joint meetings with microbicide developers supported by NIAID and IPM.

NIAID brings funding resources and expertise in topical microbicide discovery and early product development for HIV and other STIs to the partnership, while IPM has enhanced capacity to design optimal microbicide formulations, manufacture pilot lots of microbicides for clinical testing and implement clinical trials, says Roberta Black, PhD, NIAIDs topical microbicide team leader. The relationship between NIAID and IPM, adds Black, should help accelerate the advance of selected candidate microbicides through key steps, such as formulation optimization, process development and scale-up for manufacture, in the research and development pathway.

Source: National Institutes of Health

 

 

Related Videos
Baby visiting a pediatric facility  (Adobe Stock 448959249 by Rawpixel.com)
Antimicrobial Resistance (Adobe Stock unknown)
Anne Meneghetti, MD, speaking with Infection Control Today
Patient Safety: Infection Control Today's Trending Topic for March
Infection Control Today® (ICT®) talks with John Kimsey, vice president of processing optimization and customer success for Steris.
Picture at AORN’s International Surgical Conference & Expo 2024
Infection Control Today and Contagion are collaborating for Rare Disease Month.
Rare Disease Month: An Infection Control Today® and Contagion® collaboration.
Vaccine conspiracy theory vector illustration word cloud  (Adobe Stock 460719898 by Colored Lights)
Related Content