New Drug Targets May Lead to Effective Ebola Treatments

Article

There are no approved treatments or preventives against Ebola virus disease, but investigators have now designed peptides that mimic the virus' N-trimer, a highly conserved region of a protein that's used to gain entry inside cells.

The team showed that the peptides can be used as targets to help researchers develop drugs that might block Ebola virus from entering into cells.

"In contrast to the most promising current approaches for Ebola treatment or prevention, which are species-specific, our 'universal' target will enable the selection of broad-spectrum inhibitors that should block all known--and likely future--Ebola strains," says Dr. Michael Kay, senior author of the Protein Science study.

Source: Wiley

Recent Videos
Pathogen Playbook Presenter: Sharon Ward-Fore, BS, MS, MT(ASCP), CIC, FAPIC
Mark Wiencek, PhD
Rebecca Crapanzano-Sigafoos, DrPH, CIC, AL-CIP, FAPIC
The CDC’s updated hospital respiratory reporting requirement has added new layers of responsibility for infection preventionists. Karen Jones, MPH, RN, CIC, FAPIC, clinical program manager at Wolters Kluwer, breaks down what it means and how IPs can adapt.
Studying for the CIC using a digital tablet and computer (Adobe Stock 335828989 by NIKCOA)
Infection Control Today's Conversations with the HSPA President, Arlene Bush, CRCST, CER, CIS, SME, DSMD, CRMST
Infection Control Today's Conversations with the HSPA President, Arlene Bush, CRCST, CER, CIS, SME, DSMD, CRMST
Cheron Rojo, BS, FCS, CHL,  CER, CFER, CRCST
Matthias Tschoerner, Dr Sc
Standardizing Cleaning and Disinfection
Related Content