Re-introducing Fosfomycin May Help Fight Multidrug-Resistant Bacteria
A new study indicates that the drug fosfomycin may be effective for treating multidrug-resistant bacterial infections.
A new study indicates that the drug fosfomycin may be effective for treating multidrug-resistant bacterial infections. In most European countries, the oral formulation is only approved as a 3 gram single dose for the treatment of uncomplicated cystitis; however the Pharmacology Research & Perspectives study found that a dosing regimen of 6-12 grams per day divided in 3 doses is required for the treatment of systemic multi-drug-resistant bacterial infections.
Fosfomycin--an 'old' antibiotic that was developed more than 40 years ago--is a broad spectrum antibiotic that inhibits the early stages of the bacterial cell wall synthesis.
"Importantly, we show that there is a viable alternative to the lengthy and thus costly development of new antibiotics. The often scattered knowledge in literature and in the clinic is waiting to be combined and can be used immediately in a confirmatory clinical trial," said senior author Dr. Jasper Stevens, of the University Medical Center Groningen, in The Netherlands.
Source: Wiley
A Controversial Reboot: New Vaccine Panel Faces Scrutiny, Support, and Sharp Divides
June 26th 2025As the newly appointed Advisory Committee on Immunization Practices (ACIP) met for the first time under sweeping changes by HHS Secretary Robert F. Kennedy Jr, the national spotlight turned to the panel’s legitimacy, vaccine guidance, and whether science or ideology would steer public health policy in a polarized era.
Getting Down and Dirty With PPE: Presentations at HSPA by Jill Holdsworth and Katie Belski
June 26th 2025In the heart of the hospital, decontamination technicians tackle one of health care’s dirtiest—and most vital—jobs. At HSPA 2025, 6 packed workshops led by experts Jill Holdsworth and Katie Belski spotlighted the crucial, often-overlooked art of PPE removal. The message was clear: proper doffing saves lives, starting with your own.
