Treatment of Humans and Pigs May Reduce Endemic Tapeworm Infection

Article

The transmission of Taenia solium, a pork tapeworm species that infects humans and causes late-onset seizures and epilepsy, can be stopped on a population-wide level with mass treatments of both pigs and humans, researchers have shown.

Researchers from several institutions, including Georgia State University, contributed to the study and published their findings in The New England Journal of Medicine.

Humans can become infected after eating contaminated pork or through fecal-oral exposure. This study was aimed at eliminating Taenia solium from the villages of Tumbes Province in Peru, a highly endemic region for the disease.

Researchers screened and treated pigs and humans in the first two phases of the program. In the final phase, mass treatment was given to 81,170 people in 107 villages, and 55,638 pigs received treatment and vaccination. Mass treatment included chemotherapy with niclosamide in humans and with oxfendazole in pigs, in combination with pig vaccination.

The researchers found only three of 342 pigs had live, nondegenerated cysts, but no infected pigs were found in 105 of 107 villages. The researchers showed the transmission of Taenia solium infection can be interrupted on a regional scale in a highly endemic region.

The researchers say they expect this effect will only be temporary if it is not bolstered by additional activities.

Source: Georgia State University 

Newsletter

Stay prepared and protected with Infection Control Today's newsletter, delivering essential updates, best practices, and expert insights for infection preventionists.

Recent Videos
Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
© 2025 MJH Life Sciences

All rights reserved.