
After identifying 2 colon surgical site infections in 2024, Orlando Health South Lake Hospital implemented a standardized perioperative checklist to improve adherence with colorectal SSI prevention practices. Presented at APIC 2026, the project increased appropriate antibiotic prophylaxis, reduced inappropriate antibiotic use, maintained 100% adherence with clean-dirty instrument protocols, and was associated with the elimination of additional colon SSIs during 2025.




























