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In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a drug designed to thwart it. This achievement sets the stage to use X-ray crystallography to develop complete images of HIV that include integrase, which in turn will help scientists develop new treatments for the illness.

There’s a good reason people over 60 are not donor candidates for bone marrow transplantation. The immune system ages and weakens with time, making the elderly prone to life-threatening infection and other maladies, and a UC San Francisco research team now has discovered a reason why.