CDC and Partners Investigate Newly Discovered Virus

Bourbon virus. Image courtesy of the CDC.

The Centers for Disease Control and Prevention (CDC) is today reporting on the discovery of a new virus that may have contributed to the death of a previously healthy man in eastern Kansas in late spring 2014. A CDC study published today details the progression of the man’s illness and actions taken by CDC, the Kansas Department of Health and Environment (KDHE), and University of Kansas Medical Center (UKMC) to treat and investigate the case. The virus, named Bourbon virus for the county where the patient lived, is part of a group of viruses called thogotoviruses. This is the first time a virus in this group has been shown to cause human illness in the United States and only the eighth known case of thogotoviruses causing symptoms in people.
                       
The article was published today in CDC’s Emerging Infectious Diseases journal and is available at: http://wwwnc.cdc.gov/eid/article/21/5/15-0150_article.

Since viruses in this group (thogotoviruses) have been linked to ticks or mosquitoes in parts of Europe, Asia, and Africa, Bourbon virus might also be spread through tick or other insect bites. The Kansas man had received multiple tick bites in the days before becoming ill. After test results for many infectious diseases came back negative, a sample of the patient’s blood was sent to the CDC for additional testing. Initial CDC testing showed evidence of an unidentified virus in the sample. CDC researchers then used Advanced Molecular Detection (AMD) and determined that it was a new virus.

The CDC is collaborating with KDHE and UKMC to identify additional cases of Bourbon virus disease, determine who gets sick and with what symptoms, and how people are getting infected. CDC experts will also be working in the lab to better understand the virus itself, how it makes people sick, and what animals (if any) may play a role in its spread. This information will help determine the best ways to potentially prevent and control Bourbon virus.
                                                                                  
The discovery of Bourbon virus, as well as the recent discoveries of Heartland virus in Missouri and severe fever with thrombocytopenia syndrome viruses in China, leads CDC researchers to believe that other undiscovered viruses are likely causing people to get sick. Use of AMD methods in laboratories across the world is an important tool for  discovering and addressing new pathogens.

For more information on Bourbon virus, visit http://www.cdc.gov/ncezid/dvbd/bourbon/index.html.