Bacteria go extinct at substantial rates, although appear to avoid the mass extinctions that have hit larger forms of life on Earth, according to new research from the University of British Columbia (UBC), Caltech, and Lawrence Berkeley National Laboratory. The finding contradicts widely held scientific thinking that microbe taxa, because of their very large populations, rarely die off.
The study, published today in Nature Ecology and Evolution, used massive DNA sequencing and big data analysis to create the first evolutionary tree encompassing a large fraction of Earth's bacteria over the past billion years.
"Bacteria rarely fossilize, so we know very little about how the microbial landscape has evolved over time," says Stilianos Louca, a researcher with UBC's Biodiversity Research Centre who led the study. "Sequencing and math helped us fill in the bacterial family tree, map how they've diversified over time, and uncover their extinctions."
Louca and colleagues estimate between 1.4 and 1.9 million bacterial lineages exist on Earth today. They were also able to determine how that number has changed over the last billion years--with 45,000 to 95,000 extinctions in the last million years alone.
"While modern bacterial diversity is undoubtedly high, it's only a tiny snapshot of the diversity that evolution has generated over Earth's history," says Louca.
Despite the frequent, steady extinction of individual species, the work shows that--overall--bacteria have been diversifying exponentially without interruption. And they've avoided the abrupt, planet-wide mass extinctions that have periodically occurred among plants and animals. Louca suspects that competition between bacterial species drive the high rate of microbial extinctions, leaving them less prone to sudden mass, multi-species extinctions.
Past speciation and extinction events leave a complex trace in phylogenies--mathematical structures that encode the evolutionary relatedness between existing bacterial species.
"This study wouldn't have been possible 10 years ago," says Michael Doebeli, UBC mathematician and zoologist, and senior author on the paper. "Today's availability of massive sequencing data and powerful computational resources allowed us to perform the complex mathematical analysis."
Next, Louca and his colleagues want to determine how the physiological properties of bacteria evolve over time, and whether their ecological diversity has also been increasing similarly to their taxonomic diversity. If this is true, it would mean that even ancient and relatively simple organisms such as bacteria still have the potential to discover novel ways to survive.
Source: University of British Columbia
CDC Urges Vigilance: New Recommendations for Monitoring and Testing H5N1 Exposures
July 11th 2025With avian influenza A(H5N1) infections surfacing in both animals and humans, the CDC has issued updated guidance calling for aggressive monitoring and targeted testing to contain the virus and protect public health.
IP LifeLine: Layoffs and the Evolving Job Market Landscape for Infection Preventionists
July 11th 2025Infection preventionists, once hailed as indispensable during the pandemic, now face a sobering reality: budget pressures, hiring freezes, and layoffs are reshaping the field, leaving many IPs worried about their future and questioning their value within health care organizations.
A Helping Hand: Innovative Approaches to Expanding Hand Hygiene Programs in Acute Care Settings
July 9th 2025Who knew candy, UV lights, and a college kid in scrubs could double hand hygiene adherence? A Pennsylvania hospital’s creative shake-up of its infection prevention program shows that sometimes it takes more than soap to get hands clean—and keep them that way.