InVision-Plus Benefits Shown by Study Presented at European Oncology Nursing Society


RyMed Technologies, Inc. announces that InVision-Plus® with Neutral Advantage Technology outperformed a negative pressure,split-septum needleless IV connector in a prospective study that examined the association of different IV connector types with catheter-related bloodstream infection (CRBSI) rates.  

The infection rates were observed to drop dramatically when two oncology departments at a major U.S. cancer hospital switched from a negative pressure, split-septum needleless IV connector to the RyMed InVision-Plus. After the switch to InVision-Plus, the incidence of CRBSI dropped 96.5 percent in one of the departments and 89.2 percent in the other.
The results were reported in a scientific poster presented at the recent 8th European Oncology Nursing Society (EONS) Spring Convention. The authors of the poster are Cynthia Chernecky, PhD, RN, AOCN, FAAN, of Georgia Health Sciences University, Augusta, Ga.; William R. Jarvis, MD, of Jason & Jarvis Associates, LLC, Hilton Head Island, S.C.; and Denise Macklin, BSN, RN-C, Marietta, Ga.
InVision-Plus is referred to as an "intraluminal protection device (IPD)" in the poster.
"The message here is clear: the needleless IV connector type matters," says Chernecky. "The biggest advantages of the IPD connector design are its zero fluid displacement, straight fluid pathway and the absence of dead space in the fluid pathway." 
Fluid pathway issues pose problems for other types of IV connectors. Chernecky says. "The complicated fluid pathways, blood reflux issues and dead space of other IV connectors promote biofilm formation. This helps explain why those connectors are associated with higher CRBSI rates, in our studies and elsewhere. The advantages of the IPD appear to be so great that similar IV connectors should be considered central to any CRBSI prevention initiative." 
The same poster also reported results from a second study, in which InVision-Plus significantly outperformed two other needleless IV connector types. This study, performed in vitro, compared the ability of three IV connector types, including InVision-Plus, to resist bacteria that commonly cause CR-BSI. 
During the 96-hour test period, enough bacteria to cause a CR-BSI were found on 65 percent of the negative pressure split-septum IV connectors tested and on 30 percent of the positive pressure IV connectors tested. 
InVision-Plus has numerous characteristics designed to prevent infections including double microbial barrier, excellent septum seal integrity, zero fluid displacement, a straight fluid pathway and no dead space. Thus, it is easier to completely flush blood from the IV connector/catheter when InVision-Plus is used.  
The FDA has issued an alert requiring all manufacturers of positive pressure connectors to assess whether their devices do not increase CRBSI risk. This is because numerous studies already associate positive pressure connectors with higher rates of CRBSI.
Jarvis has noted in a previous publication that studies also associate negative pressure IV connectors with higher CRBSI rates, due in part to greater rates of occlusion.
The 8th European Oncology Nursing Society (EONS) Spring Convention was held April 26-27 in Geneva, Switzerland. 

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