Researchers at Duke University Medical Center may have a new way to stop and even prevent the urinary tract infections (UTIs) that plague more than one-third of all adults, some of them repeatedly.
The researchers have discovered how cells within the bladder are able to sense the presence of E. coli bacteria hiding within compartments in the bladder's own cells. This starts a process that then kicks them out.
Knowing how the bladder's own cells sense the bacteria and what they do to expel them are both processes the Duke scientists think they can exploit to do a better job of helping the bladder protect itself. New treatments based on their findings might be able to tackle antibiotic-resistant UTIs and perhaps even bacterial infections in other parts of the body, said Soman Abraham, a professor of pathology at Duke.
The findings appear in the Proceedings of the National Academy of Sciences.
Endoscopes and Lumened Instruments: New Studies Highlight Persistent Contamination Risks
May 7th 2025Two new studies reveal troubling contamination in both new endoscopes and cleaned lumened surgical instruments, challenging the reliability of current reprocessing practices and manufacturer guidelines.
Happy Hand Hygiene Day! Rethinking Glove Use for Safer, Cleaner, and More Ethical Health Care
May 5th 2025Despite their protective role, gloves are often misused in health care settings—undermining hand hygiene, risking patient safety, and worsening environmental impact. Alexandra Peters, PhD, points out that this misuse deserves urgent attention, especially today, World Hand Hygiene Day.