Oseltamivir-Resistant Novel Influenza A (H1N1) Virus Infection

The MMWR Dispatch (Vol. 58) is reporting that on Aug. 6, 2009, the Centers for Disease Control and Prevention (CDC) detected evidence of resistance to the antiviral medication oseltamivir by pyrosequencing viral RNA from clinical specimens of two immunosuppressed patients with novel influenza A (H1N1) virus infection in Seattle. This report summarizes the case histories and resulting investigations and highlights the importance of close monitoring for antiviral drug resistance among immunosuppressed patients receiving treatment for novel influenza A (H1N1) virus infection, plus the implications for infection prevention and control. To read the full report from the MMWR, CLICK HERE.