Priorities on Dealing with the 'Big Three' Infectious Diseases: HIV/AIDS, Tuberculosis and Malaria

David Molyneux, a professor at the the Liverpool School of Tropical Medicine, Liverpool, England, outlines how priorities on dealing with the big 3 infectious diseases -- HIV/AIDS, tuberculosis, and malaria -- is obstructing public health initiatives to tackle preventable diseases such as the viral, bacterial, and parasitic infections of the tropics, and acute respiratory infections and diarrheal diseases of children. Examples are given of numerous cost-effective treatment programs for diseases such as onchocerciasis (river blindness) and Chagas disease.

Molyneux comments, The emphasis on the 'Big Three' killers and the derogatory assignment to the category of other diseases of those that can so easily be controlled or even eliminated, neglects the proven success of a range of interventions. An investment of a fraction of the annual requirements of the global fund would bring long-lasting benefit to the millions that still remain disabled, reduce morbidity, and prevent disablement in future generations. If we are to ensure the efficient use of the substantial resources needed to reduce morbidity and mortality associated with HIV/AIDS, tuberculosis, and malaria, then a small investment in proven, cost-effective interventions against other diseases -- preferably from the global fund resources -- will bring sustainable public-health benefits, integrate well with and strengthen the health system, reduce disabling conditions, and bring collateral benefits to the health of the poorest nations.