What is Clean? By Malcolm Smith
By strict definition, “clean” is the absence of unwanted matter. That said, the scope of work ultimately defines it. As quality expert W. Edwards Deming illustrated, cleaning a table in a restaurant differs from cleaning an operating room (OR) table; so “clean” is defined by the system's aim.
Since we are promoting the Bioload Exposure Metric Index (BEMI) as a proxy for overall surface contamination (not including specific pathogens), the “cleaning” aim is to reduce adenosine triphosphate (ATP) levels.
Of course, while ATP devices commonly measure a single energy molecule (ATP), newer technology measures 3 molecules: ATP, ADP (adenosine diphosphate), and AMP (adenosine monophosphate), providing a broader, more precise assessment of organic contamination.
This is helpful because ATP breaks down quickly over time or when exposed to certain environments, transforming into ADP and AMP.








