Salmonella May Be Good?

Article

Research Shows It Inhibits Tumors in Mice

WASHINGTON, DC-Researchers at Yale University and Vion Pharmaceuticals have found that strains of Salmonella enterica serovar Typhimurium can live on nutrients found in malignant tumors in mice and create substances that inhibit those tumors. The American Society for Microbiology (ASM) reports that this microbially based approach to antitumor therapy, patented by Yale University and licensed to Vion Pharmaceuticals, is being adapted as a potential treatment for cancer patients.

Initial tests implanted mice with melanoma tumors. After one month, mice that had been treated with Salmonella strains had noticeably smaller tumors than the untreated mice. In addition, mice treated with the bacteria lived about 53 days, twice as long as the untreated mice.

Researchers have yet to discover how Salmonella locates a tumor and what nutrients in the tumor enable it to thrive.

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Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
Brenna Doran PhD, MA, hospital epidemiology and infection prevention for the University of California, San Francisco, and a coach and consultant of infection prevention; Jessica Swain, MBA, MLT, director of infection prevention and control for Dartmouth Health in Lebanon, New Hampshire; and Shanina Knighton, associate professor at Case Western Reserve University School of Nursing and senior nurse scientist at MetroHealth System in Cleveland, Ohio
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