Research Shows It Inhibits Tumors in Mice
WASHINGTON, DC-Researchers at Yale University and Vion Pharmaceuticals have found that strains of Salmonella enterica serovar Typhimurium can live on nutrients found in malignant tumors in mice and create substances that inhibit those tumors. The American Society for Microbiology (ASM) reports that this microbially based approach to antitumor therapy, patented by Yale University and licensed to Vion Pharmaceuticals, is being adapted as a potential treatment for cancer patients.
Initial tests implanted mice with melanoma tumors. After one month, mice that had been treated with Salmonella strains had noticeably smaller tumors than the untreated mice. In addition, mice treated with the bacteria lived about 53 days, twice as long as the untreated mice.
Researchers have yet to discover how Salmonella locates a tumor and what nutrients in the tumor enable it to thrive.
Beyond the Surface: Rethinking Environmental Hygiene Validation at Exchange25
June 30th 2025Environmental hygiene is about more than just shiny surfaces. At Exchange25, infection prevention experts urged the field to look deeper, rethink blame, and validate cleaning efforts across the entire care environment, not just EVS tasks.
A Controversial Reboot: New Vaccine Panel Faces Scrutiny, Support, and Sharp Divides
June 26th 2025As the newly appointed Advisory Committee on Immunization Practices (ACIP) met for the first time under sweeping changes by HHS Secretary Robert F. Kennedy Jr, the national spotlight turned to the panel’s legitimacy, vaccine guidance, and whether science or ideology would steer public health policy in a polarized era.
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