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Every day, infection preventionists (IPs) and other healthcare personnel face significant challenges due to evolving technology, healthcare reform and, of course, time constraints. Choosing the right disinfectant products must be a carefully made decision but it shouldnt be burdensome. Yet, because healthcare products are continually being released, updated and retired from the marketplace, IPs would be challenged to monitor the status of every single item within their facilities. This article will provide a methodical approach to evaluate and effectively use healthcare disinfectants.