Zika Antibodies From Infected Patient Thwart Infection in Mice
December 15th 2016Researchers have identified neutralizing antibodies against Zika virus from an infected patient that fully protected mice from infection, adding to the current arsenal of antibodies in development for much needed antiviral therapies and vaccines. Unlike other human antibodies under investigation that recognize both Zika and the closely related dengue virus, the antibodies used in this study exclusively target Zika, demonstrating a high specificity that could be important in avoiding potential side effects - such as enhanced dengue infection in regions where both viruses are endemic.
Epidemiologist Joins UN Expert Mission to Confront Rift Valley Fever Outbreak
December 15th 2016A Rift Valley fever outbreak was recently reported at the border between Niger and Mali in West Africa. So far, 64 human cases including 23 deaths have been confirmed in Niger, according to the World Health Organization (WHO). Umeå University infectious disease epidemiologist Osama Ahmed Hassan recently joined an international expert fact-finding mission to Mali as a consultant with the Food and Agricultural Organization of the United Nations (FAO/UN).
Psychologists Analyze Links Between Provider Burnout, Quality of Care and Patient Safety
December 14th 2016Healthcare provider burnout is known to have a relationship with both quality of care and patient safety. Psychologists from the School of Science at Indiana University-Purdue University Indianapolis conducted the first study to systematically, quantitatively analyze the links between healthcare provider burnout and healthcare quality and safety across medical disciplines.
OpenNotes Reporting Tool Engages Patients as Safety Partners
December 14th 2016OpenNotes evidence has shown that transparent medical records can increase patient engagement - patients who read the clinical notes written by their doctors report feeling more in control of their care and being better able to adhere to the treatment plan. Now new research from OpenNotes investigators at Beth Israel Deaconess Medical Center (BIDMC) suggests that offering patients a mechanism to provide feedback about their notes further enhances engagement and can improve patient safety. The study results appear online today in the British Medical Journal (BMJ) Quality and Safety.
ECDC Says Efforts Needed to Stop the Spread of Carbapenem-Resistant Acinetobacter baumannii
December 14th 2016Acinetobacter baumannii is the cause of difficult-to-treat infections in healthcare settings in Europe due to its increasing resistance to antimicrobial agents, in particular the carbapenems. Outbreaks of carbapenem-resistant A. baumannii in healthcare facilities have been reported in Europe and worldwide.
UAB Performs Deep South's First HIV-Positive Kidney Transplant From HIV-Positive Deceased Donor
December 14th 2016Sometime in the next few days or weeks - whenever he can adequately gather his thoughts - a Mississippi man plans to sit down and write a very important letter to a family he has never met, but whose legacy he will carry with him for the rest of his life. The man, who is HIV-positive, is in his 30s and wishes to remain anonymous. He recently became the eighth patient in the United States to receive a transplant from an HIV-positive deceased donor. The HIV-positive to HIV-positive transplant happened at the University of Alabama at Birmingham. UAB Hospital is the first in the Deep South to achieve an HIV-positive to HIV-positive transplant, and only the fourth hospital in the country to do so.
Public Skepticism Would Likely Greet a New Zika Vaccine, UGA Study Says
December 13th 2016As scientists race to create a vaccine for the Zika virus, new research from the University of Georgia suggests almost half of Americans wouldn’t be interested in getting the shot even if public health officials recommended it for them. Only 1 in 3 people in an October 2016 nationally representative survey said they would be willing to get a Zika shot if one were available and recommended. More than two out of five respondents said they would not be interested in getting a Zika vaccine, and another quarter were undecided on the question.
Mutations Acquired Trans-Pacific May Be Key to Changes in Zika Severity
December 13th 2016The Zika virus remains a mystery. Isolated from macaque monkeys in the Ziika Forest in Uganda in 1947, the virus was shown to infect humans not long after, but it was identified as a benign disease, with mild symptoms. For this reason, it was not heavily studied until almost 70 years later when it appeared to be associated with an unusual cluster of cases of microcephalic birth defects and Guillain-Barré Syndrome (GBS) paralysis in Brazil in 2015 and 2016.