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Every two seconds, someone in the United States needs blood. In fact, more than 5 million Americans receive blood transfusions each year, according to the American Red Cross. Depending on the amount and age of the stored blood used, there is evidence that transfusion can lead to complications including infection, organ failure and death.

Researchers from the University of California, Irvine, with assistance from the San Diego Supercomputer Center at UC San Diego, have found a new approach to the creation of customized therapies for virulent flu strains that resist current antiviral drugs. The findings, published online this week in Nature Communications, could aid development of new drugs that exploit so-called flu protein pockets.