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While vancomycin-resistant enterococci (VRE) have triggered multiple outbreaks, VRE of genotype vanC appear not to be associated with outbreaks, according to Sutter, et al. (2010).

Antimicrobial resistance, the ability of microorganisms to find ways to evade the action of the drugs used to cure the infections they cause, is increasingly recognized as a global public health issue which could hamper the control of many infectious diseases.