Antibody Test Gauges Mosquito Exposure
December 1st 2016How many mosquitoes live in your neighborhood? How many mosquito bites have you and your neighbors gotten this week? Answering these questions--and gauging how mosquito populations change over time or after a control strategy is implemented--has historically been difficult. Now, researchers reporting in PLOS Neglected Tropical Diseases have described a blood test that can be used to assess human exposure to Aedes mosquitos. The test, which measures antibodies to an Aedes salivary peptide, showed decreased human exposure to mosquito bites after a vector control program.
Research Team Discovers a Pathogen's Motility Triggers Immune Response
December 1st 2016Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response. The team, led by Balázs Rada, an assistant professor in the department of infectious diseases in the UGA College of Veterinary Medicine, studied Pseudomonas aeruginosa, an opportunistic bacterium that can wreak havoc on patients who have a weakened immune system--like burn patients or those battling HIV, cystic fibrosis, cancer or pneumonia.
Flu Forecasts on Neighborhood Level are Successful
November 30th 2016Scientists at Columbia University's Mailman School of Public Health developed a computer model to predict the onset, duration, and magnitude of influenza outbreaks for New York City boroughs and neighborhoods. They found the model effective in a test using data from 2008-2013; results appear in the journal PLOS Computational Biology.
Genomics Technique Could Accelerate Detection of Foodborne Bacterial Outbreaks
November 30th 2016A new testing methodology based on metagenomics could accelerate the diagnosis of foodborne bacterial outbreaks, allowing public health officials to identify the microbial culprits in less than a day. The methodology could also identify co-infections with secondary microbes, determine the specific variant of the pathogen, and help alert health officials to the presence of new or unusual pathogens.
Researchers Tweak Enzyme 'Assembly Line' to Improve Antibiotics
November 29th 2016Researchers from North Carolina State University have discovered a way to make pinpoint changes to an enzyme-driven "assembly line" that will enable scientists to improve or change the properties of existing antibiotics as well as create designer compounds. The work is the first to efficiently manipulate which building blocks the enzyme selects in the act of synthesizing erythromycin, an important antibiotic.
WHO Issues New Guidance on HIV Self-Testing Ahead of World AIDS Day
November 29th 2016In advance of World AIDS Day, Dec. 1, 2016, the World Health Organization (WHO) has released new guidelines on HIV self-testing to improve access to and uptake of HIV diagnosis. According to a new WHO progress report, lack of an HIV diagnosis is a major obstacle to implementing the organization’s recommendation that everyone with HIV should be offered antiretroviral therapy (ART).
1 in 7 People Living With HIV in the EU are Not Aware of Their HIV Status
November 29th 2016With 29,747 newly reported HIV infections in 2015, the EU/EEA notification rate is similar to recent years with an overall insignificant change from 6.6 per 100,000 population in 2006 to 6.3 in 2015 (adjusted for reporting delay).
Researchers Develop Novel Wound-Healing Technology
November 29th 2016A Washington State University (WSU) research team has successfully used a mild electric current to take on and beat drug-resistant bacterial infections, a technology that may eventually be used to treat chronic wound infections. The researchers report on their work in the online edition of npj Biofilms and Microbiomes.