Loyola Study Reveals How HIV Enters Cell Nucleus
June 21st 2016Loyola University Chicago scientists have solved a mystery that has long baffled HIV researchers: How does HIV manage to enter the nucleus of immune system cells? The discovery, reported in the journal PLOS Pathogens, could lead to effective new drugs to treat HIV/AIDS, said Edward M. Campbell, PhD, corresponding author of the study. Campbell is an associate professor in the Department of Microbiology and Immunology of Loyola University Chicago Stritch School of Medicine.
Microbiota Affect the Rate of Transplant Acceptance and Rejection
June 21st 2016Researchers from the University of Chicago have shown that microbiota-the bacteria, viruses and other microbes living on the skin and in the digestive system-play an important role in the body’s ability to accept transplanted skin and other organs.
Infection Prevention Programs: Promoting Value, Securing Resources
June 20th 2016Promoting the value of infection prevention programs and securing the resources necessary to ensure the continued viability of such programs has become an imperative for the infection preventionist (IP) in the era of healthcare reform and increased demands on IPs' time. A new guidance document aims to provide an updated assessment of the resources and requirements for an effective infection prevention and control/healthcare epidemiology (IPC/HE) program.
Measles, Mumps and Missing the Moment
June 20th 2016From the front of the hospital classroom I saw the indifferent stares of 30 nurse residents. These first year nurses were participating in an employer sponsored program to facilitate their transition into clinical role as well as to support retention which is often unfortunately poor during this critical period in a professional RN career. However well-intended the residency program was, the lack of enthusiasm for my upcoming infection prevention update was unmistakable. As a long-time infection preventionist (IP), this was not particularly surprising, as few trainees seek out prevention content unless there is an imminent threat or some other infectious crisis. Overcoming such learner apathy – including the anticipated “we’ve heard this all before” attitude – is endemic to the infection prevention educational environment.
Survey Suggests Many Americans Don't Consider Antibiotic Resistance to be an Important Issue
June 17th 2016A new survey published in Open Forum Infectious Diseases suggests that many Americans don’t consider antibiotic resistance to be an important problem or fully grasp how resistance develops. A majority of survey respondents agreed that inappropriate antibiotic use contributes to antibiotic resistance (92 percent) while (70 percent) responded neutrally or disagreed with the statement that antibiotic resistance is a problem.
ECDC Rapid Risk Assessment Outlines Actions to Reduce the Spread of the mcr-1 Gene
June 17th 2016The recently recognized global distribution of the mcr-1 gene poses a substantial public health risk to the EU/EEA, asserts the European Centre for Disease Prevention and Control (ECDC). The gene is widespread in several continents and has been detected in bacteria isolated from multiple different sources such as food-producing animals, food, the environment and humans.
Sandia Researchers Discover Mechanism for Rift Valley Fever Virus Infection
June 16th 2016Viruses can't live without us -- literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks. Rift Valley fever virus (RVFV) and other members of the bunyavirus family may soon be added to the list of viruses denied access to a human host. Sandia National Laboratories researchers have discovered a mechanism by which RVFV hijacks the host machinery to cause infection. This mechanism offers a new approach toward developing countermeasures against this deadly virus, which in severe human infections causes fatal hepatitis with hemorrhagic fever, encephalitis and retinal vasculitis.